Evidence map›Paper›PMID 38193657›Full record

ArticlemBio2024

Genetic analysis reveals a robust and hierarchical recruitment of the LolA chaperone to the LolCDE lipoprotein transporter.

Kelly M Lehman, Kerrie L May, Julianna Marotta, Marcin Grabowicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. ThemBio · 2026
    Article
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kelly M Lehman *Microbiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
Kerrie L May *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-4302-2440
Julianna MarottaMicrobiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
Marcin GrabowiczDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0001-8000-2222

Funding

Lipoprotein trafficking to the bacterial outer membraneR35GM133509 · NIGMS · EMORY UNIVERSITY · PI GRABOWICZ, MARCIN · 2019 to 2023
$1.9M
A novel transport pathway for outer membrane lipoproteins in Gram-negative bacteriaF31AI147589 · NIAID · EMORY UNIVERSITY · PI LEHMAN, KELLY MARIE · 2020 to 2022
$115k
NIAID NIH HHS F31 AI147589NIGMS NIH HHS R35 GM133509
6 · The paper itself

Abstract

The outer membrane (OM) is an essential organelle of Gram-negative bacteria. Lipoproteins are key to building the OM, performing essential functions in several OM assembly machines. Lipoproteins mature in the inner membrane (IM) and are then trafficked to the OM. In

Indexed as

Escherichia coli ProteinsPeriplasmic Binding ProteinsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsEscherichia coliGram-Negative BacteriaLipoproteinsMembrane Transport ProteinsMolecular ChaperonesAnti-Bacterial AgentsBacterial Outer Membrane ProteinsEscherichia coli ProteinsLipoproteinsLolA protein, E coliMembrane Transport ProteinsMolecular ChaperonesPeriplasmic Binding Proteinslipoproteinlipoprotein traffickingLolALolCLolCDEouter membrane

Identifiers

PMID38193657
PMCPMC10865981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.