Evidence map›Paper›PMID 38193543›Full record

ArticleeLife2024

Balance of activity during a critical period tunes a developing network.

Iain Hunter, Bramwell Coulson, Tom Pettini, Jacob J Davies, Jill Parkin, Matthias Landgraf, Richard A Baines

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. More Than a Small Brain: The Importance of Studying Neural Function during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Iain Hunter *Division of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health,University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0002-4506-9349
Bramwell Coulson *Division of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health,University of Manchester, Manchester, United Kingdom.
Tom PettiniDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Jacob J DaviesDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health,University of Manchester, Manchester, United Kingdom.
Jill ParkinDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health,University of Manchester, Manchester, United Kingdom.
Matthias LandgrafDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-5142-1997
Richard A BainesDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health,University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0001-8571-4376
University of Cambridge · GB

Funding

Wellcome TrustWellcome Trust Grant 217099/Z/19/Z
6 · The paper itself

Abstract

Developing neural circuits are influenced by activity and are especially sensitive to changes in activity during critical periods (CPs) of development. Changes occurring during a CP often become 'locked in' so that they affect the mature network. Indeed, several neurodevelopmental disorders have been linked to excessive activity during such periods. It is, therefore, important to identify those aspects of neural circuit development that are influenced by neural activity during a CP. In this study, we take advantage of the genetic tractability of

Indexed as

DrosophilaNeurodevelopmental DisordersAnimalsInhibition, PsychologicalMotor NeuronsMutationcritical periodD. melanogasterhomeostasislocomotionmotor systemnetworkneuroscience

Identifiers

PMID38193543
PMCPMC10945558
OpenAlexW4387333906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.