Evidence map›Paper›PMID 38193509›Full record

ArticleCurrent medical research and opinion2024

Sociodemographic disparities in GLP-1RA and SGLT2i use among US adults with type 2 diabetes: NHANES 2005-March 2020.

Benjamin G Mittman, Phuc Le, Julia Y Payne, Gina Ayers, Michael B Rothberg

Abstract read
In one paragraph

Article in Current medical research and opinion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  18. Achieving equitable access to incretin-based therapies in cardiovascular care.American heart journal plus : cardiology research and practice · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin G MittmanCenter for Value-Based Care Research, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-7721-5822
Phuc LeCenter for Value-Based Care Research, Cleveland Clinic, Cleveland, OH, USA.
Julia Y PayneCenter for Value-Based Care Research, Cleveland Clinic, Cleveland, OH, USA.
Gina AyersDepartment of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, OH, USA.
Michael B RothbergCenter for Value-Based Care Research, Cleveland Clinic, Cleveland, OH, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Medical Scientist Training Program at Case Western Reserve UniversityT32GM152319 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Heather Broihier, Alex Yee-Chen Huang · 2024 to 2026
$5.1M
NRSA Training CoreTL1TR002549 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI HARDING, CLIFFORD V · 2018 to 2022
$2.9M
NCATS NIH HHS TL1 TR002549NIGMS NIH HHS T32 GM007250NIGMS NIH HHS T32 GM152319
6 · The paper itself

Abstract

objectiveType 2 Diabetes (T2D) is a major cause of morbidity and mortality. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are highly effective but underutilized. Our objective was to assess racial/ethnic and other sociodemographic disparities in GLP-1RA/SGLT2i use among US adults with T2D.

methodsWe conducted a retrospective analysis using the National Health and Nutrition Examination Survey from 2005-March 2020. Participants were adults with T2D taking ≥1 anti-diabetic medication, excluding pregnant women and adults with probable T1D. We performed univariate analyses to examine the characteristics of patients using GLP-1RA/SGLT2i and multivariable logistic regression to assess disparities in GLP-1RA/SGLT2i use after adjusting for other patient factors.

resultsAmong 4777 people with T2D (representing >18 million US adults) taking ≥1 medication, GLP-1RA/SGLT2i usage increased from 1.4% in 2005-2006 to 13.3% in 2017-2020. In univariate analyses, patients using GLP-1RA/SGLT2i vs. other T2D drugs were more likely to be White than nonwhite (72% vs. 60%,

conclusionsThe use of GLP-1RA/SGLT2i drugs increased over time but remained low in March 2020. Higher education and income, but not race/ethnicity, were associated with GLP-1RA/SGLT2i use.

Indexed as

Diabetes Mellitus, Type 2Sodium-Glucose Transporter 2 InhibitorsAdultFemaleGlucagon-Like Peptide-1 ReceptorHumansHypoglycemic AgentsIncomeNutrition SurveysPregnancyRetrospective StudiesGlucagon-Like Peptide-1 ReceptorHypoglycemic AgentsSodium-Glucose Transporter 2 InhibitorsdiabetesDisparitiesGLP-1RANHANESSGLT2i

Identifiers

PMID38193509
PMCPMC10947468

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.