ArticleJournal of the American Heart Association2024
Common Heart Failure With Preserved Ejection Fraction Animal Models Yield Disparate Myofibril Mechanics.
Open access · goldAbstract read
In one paragraph
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 6 citations in OpenAlex.
- Diastolic contributors in cardiomyocytes of a cardiometabolic HFpEF-like mouse model.The Journal of general physiology · 2026Article
- Clinical trials in a dish: cardiometabolic drug development with biological and digital twins.The Journal of clinical investigation · 2026Review
- Severe obesity in human HFpEF alters contractile protein function and organization.Science (New York, N.Y.) · 2026Article
- Cardiorenal Syndrome and Autonomic Overactivity.Biomedicines · 2025Review
- In Vitro Modeling of Interorgan Crosstalk: Multi-Organ-on-a-Chip for Studying Cardiovascular-Kidney-Metabolic Syndrome.Circulation research · 2025Review
- Metabolic Reprogramming in Heart Failure: From Energy Starvation to Therapeutic Targets.Current treatment options in cardiovascular medicine · 2025Review
- Cardiomyocyte myofilament function in common animal models of heart failure with preserved ejection fraction.Journal of molecular and cellular cardiology · 2024Article
- Early pathological mechanisms in a mouse model of heart failure with preserved ejection fraction.American journal of physiology. Heart and circulatory physiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Axel J FenwickDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-8296-537X
Vivek P JaniDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-3811-4973
D Brian FosterDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-9290-9590
Thomas E SharpDepartment of Molecular Pharmacology and Physiology University of South Florida Tampa FL USA.ORCID 0000-0001-8706-9825
Traci T GoodchildDepartment of Cardiac Surgery Smidt Heart Institute, Cedars-Sinai Medical Center Los Angeles CA USA.
Kyle LaPennaDepartment of Medicine, Cardiovascular Center of Excellence Louisiana State University Health Sciences Center New Orleans LA USA.ORCID 0000-0003-0470-0138
Jake E DoironDepartment of Medicine, Cardiovascular Center of Excellence Louisiana State University Health Sciences Center New Orleans LA USA.ORCID 0000-0002-4584-4819
David J LeferDepartment of Cardiac Surgery Smidt Heart Institute, Cedars-Sinai Medical Center Los Angeles CA USA.ORCID 0000-0003-2293-7278
Joseph A HillDepartment of Medicine UT Southwestern Medical Center Dallas TX USA.ORCID 0000-0002-5379-1614
David A KassDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0003-1596-2299
Anthony CammaratoDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0003-1104-4407
Johns Hopkins University · USCedars-Sinai Medical Center · USLouisiana State University Health Sciences Center New Orleans · USSouthwestern Medical Center · USUniversity of South Florida · US
Funding
PATHOPHYSIOLOGY OF MYOCARDIAL DISEASEST32HL007227 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Chulan Kwon, WENDY S POST · 1985 to 2026
$21.2MLeveraging Protein Kinase G-1 Nanodomain Control and Molecular Targeting to Enhance its Therapeutic Use Against Myocardial DiseaseR35HL135827 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KASS, DAVID ALAN · 2017 to 2023
$6.3MPATHOGENESIS AND IN VIVO SUPPRESSION OF THIN FILAMENT-BASED CARDIOMYOPATHIESR01HL124091 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Anthony Cammarato · 2015 to 2026
$4.3MIntersection of Obesity and Heart Failure with Preserved Ejection FractionR35HL166565 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI David Alan Kass · 2023 to 2026
$4.1MNRSA Training CoreTL1TR003106 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2019 to 2023
$3.7MRoles of Endothelial and Smooth Muscle KATP Channels in Myocardial Ischemic InjuryR01HL146514 · NHLBI · LSU HEALTH SCIENCES CENTER · PI COETZEE, WILLIAM A, LEFER, DAVID JOSEPH · 2020 to 2023
$3.0MRenal Denervation in Heart Failure with Preserved Ejection FractionR01HL159428 · NHLBI · LSU HEALTH SCIENCES CENTER · PI GOODCHILD, TRACI TAYLOR · 2021 to 2024
$2.9MRetinoid Metabolism in the Adult Heart and Heart FailureR01HL164478 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI D Brian Foster, MAUREEN A KANE · 2023 to 2026
$2.8MCardiomyocyte bromodomain protein 4 (BRD4) in physiology and diseaseR01HL147933 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2020 to 2023
$2.5METS2-dependent control in cardiomyocyte ischemia/reperfusion injuryR01HL164586 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GILLETTE, THOMAS G, HILL, JOSEPH A · 2022 to 2025
$2.5MHydrogen Sulfide Regulation in CardioprotectionR01HL151398 · NHLBI · BROWN UNIVERSITY · PI LEFER, DAVID JOSEPH, XIAN, MING · 2020 to 2023
$2.3MAlcohol-induced Gut Dysbiosis and Cardiovascular DiseaseR01AA029984 · NIAAA · UNIVERSITY OF SOUTH FLORIDA · PI Thomas E. Sharp · 2022 to 2026
$2.1MNCATS NIH HHS TL1 TR003106NHLBI NIH HHS F31 HL168850NHLBI NIH HHS R01 HL124091NHLBI NIH HHS R01 HL128215NHLBI NIH HHS R01 HL146098NHLBI NIH HHS R01 HL146514NHLBI NIH HHS R01 HL147933NHLBI NIH HHS R01 HL151398NHLBI NIH HHS R01 HL155765NHLBI NIH HHS R01 HL159428NHLBI NIH HHS R01 HL164478NHLBI NIH HHS R01 HL164586NHLBI NIH HHS R35 HL135827NHLBI NIH HHS R35 HL166565NHLBI NIH HHS T32 HL007227NIAAA NIH HHS R01 AA029984
Abstract
PubMed holds no abstract for this paper.
Indexed as
Heart FailureMyofibrilsAnimalsModels, AnimalStroke VolumeVentricular Function, Leftanimal modelsdiastoleheart failureheart failure with preserved ejection fractionmyofibril
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.