Evidence map›Paper›PMID 38193163›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024

GSK3β/NF-κB -dependent transcriptional regulation of homeostatic hepatocyte

Maya R Grayck, William C McCarthy, Mack Solar, Emma Golden, Natarajan Balasubramaniyan, Lijun Zheng, Laura G Sherlock, Clyde J Wright

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maya R GrayckSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.ORCID 0000-0001-5232-3205
William C McCarthySection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.
Mack SolarSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.
Emma GoldenSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.
Natarajan BalasubramaniyanSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.
Lijun ZhengSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.
Laura G SherlockSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.ORCID 0000-0002-0972-6663
Clyde J WrightSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States.ORCID 0000-0002-8449-5631
University of Colorado Denver · US

Funding

Research Supplement to Promote Diversity in Health Related Research: Pulmonary implications ofperinatal acetaminophen exposureR01HD107700 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Clyde Jason Wright · 2022 to 2026
$2.2M
HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R01HD107700NICHD NIH HHS R01 HD107700
6 · The paper itself

Abstract

Maintenance of hepatocyte homeostasis plays an important role in mediating the pathogenesis of many diseases. A growing body of literature has established a critical role played by tumor necrosis factor-α (TNFα) in maintaining hepatocyte homeostasis; however, the transcriptional mechanisms underlying constitutive

Indexed as

NF-kappa BTranscription Factor RelATumor Necrosis Factor-alphaAnimalsGene ExpressionGlycogen Synthase Kinase 3 betaHepatocytesHomeostasisMiceMice, Inbred C57BLGlycogen Synthase Kinase 3 betaGsk3b protein, mouseNF-kappa BRela protein, mouseTranscription Factor RelATumor Necrosis Factor-alphaGSK3βhepatocyte homeostasisNF-κBTNFαtranscriptional regulation

Identifiers

PMID38193163
PMCPMC11211040
OpenAlexW4391492888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.