ReviewInnovations in clinical neuroscience
Morphological and Functional Changes of Cerebral Cortex in Autism Spectrum Disorder.
Review in Innovations in clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 5 citations in OpenAlex.
- Oxytocin and RAGE signaling at the intersection of social neurodevelopment and inflammation.Journal of translational medicine · 2026Review
- Autism Spectrum Disorder-Associated Genes Enrich in Discrete Cortical, Limbic and Cerebellar Brain Regions.The European journal of neuroscience · 2026Article
- Lean-NET-Based Local Brain Connectome Analysis for Autism Spectrum Disorder Classification.Bioengineering (Basel, Switzerland) · 2026Article
- Integrating Brain Morphological Features and Ionized Serum Magnesium to Identify Mild Tic Comorbidity in Children with Autism Spectrum Disorder.Neuropsychiatric disease and treatment · 2026Article
- Age-stratified multimodal MRI and machine learning to explore autism-related brain characteristics in youth.Frontiers in psychiatry · 2026Article
- Subtyping Autism Spectrum Disorder With a Population Graph-Based Dual Autoencoder: Revealing Two Distinct Biotypes.CNS neuroscience & therapeutics · 2025Article
- Connections Between Prefrontal Cortex Anatomy and Autism Spectrum Disorder: A Literature Review.Acta medica academica · 2025Review
- VAE deep learning model with domain adaptation, transfer learning and harmonization for diagnostic classification from multi-site neuroimaging data.Frontiers in neuroinformatics · 2025Article
- Prenatal stress and neuroendocrine pathways framing attention-deficit/hyperactivity disorder as a functionally based neurodevelopmental disorder: a narrative review.Journal of Yeungnam medical science · 2025Article
- Drug Treatments for Neurodevelopmental Disorders: Targeting Signaling Pathways and Homeostasis.Current neurology and neuroscience reports · 2024Review
- Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.International journal of molecular sciences · 2024Article
- Compensating cortical thickness for cortical folding-related variation.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by early-onset impairments in socialization, communication, repetitive behaviors, and restricted interests. ASD exhibits considerable heterogeneity, with clinical presentations varying across individuals and age groups. The pathophysiology of ASD is hypothesized to be due to abnormal brain development influenced by a combination of genetic and environmental factors. One of the most consistent morphological parameters for assessing the abnormal brain structures in patients with ASD is cortical thickness. Studies have shown changes in the cortical thickness within the frontal, temporal, parietal, and occipital lobes of individuals with ASD. These changes in cortical thickness often correspond to specific clinical features observed in individuals with ASD. Furthermore, the aberrant brain anatomical features and cortical thickness alterations may lead to abnormal brain connectivity and synaptic structure. Additionally, ASD is associated with cortical hyperplasia in early childhood, followed by a cortical plateau and subsequent decline in later stages of development. However, research in this area has yielded contradictory findings regarding the cortical thickness across various brain regions in ASD.
Indexed as
Identifiers
38193097PMC10773605W4390706105What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.