Evidence map›Paper›PMID 38192833›Full record

ArticleHeliyon2024

Impact of CT-guided hookwire localization on tumor spread through air spaces in stage IA lung adenocarcinoma.

Xiaofan Wang, Xiaoxiao Dai, Qifeng Ding, Yi Xu, Lei Chen, Shanzhou Duan, Yongsheng Zhang, Yongbing Chen, Donglai Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaofan WangDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Xiaoxiao DaiDepartment of Pathology, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Qifeng DingDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Yi XuDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Lei ChenDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Shanzhou DuanDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Yongsheng ZhangDepartment of Pathology, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Yongbing ChenDepartment of Thoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Donglai ChenDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Soochow University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It remains undetermined whether preoperative computed tomography (CT)-guided hookwire localization would result in elevated risk of tumor spread through air spaces (STAS) in stage IA lung adenocarcinoma. Methods: A total of 1836 patients who underwent lobectomy were included. To eliminate the potential impact of confounding factors on producing STAS, propensity score-matching (PSM) was used to create two balanced subgroups stratified by implementation of hookwire localization. We also introduced an external cohort including 1486 patients to explore the effect of hookwire localization on the incidence of STAS and patient survival after sublobar resection (SR). For proactive simulation of hookwire localization, 20 consecutive lobectomy specimens of p-stage IA lung adenocarcinoma were selected. Results: Ex vivo tests revealed that mechanical artifacts presenting as spreading through a localizer surface (STALS) could be induced by hookwire localization but be distinguished by CD68 and AE1/3 antibody-based immunohistochemistry. The distance of STALS dissemination tended to be shorter compared with real STAS ( Conclusions: CT-guided hookwire localization might induce mechanical artifacts presenting as STALS which could be distinguished by immunohistochemistry, but would not affect survival in p-stage IA disease. Surgeons can be less apprehensive about performing hookwire localization in relation to STAS on stage IA disease suitable for SR.

Indexed as

CT-Guided hookwire localizationLung adenocarcinomaSpread through air spaces

Identifiers

PMID38192833
PMCPMC10772635
OpenAlexW4389855364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.