Evidence map›Paper›PMID 38192725›Full record

ArticleFrontiers in veterinary science2023

Immunoinformatics-aided rational design of a multi-epitope vaccine targeting feline infectious peritonitis virus.

Mohit Chawla, Andrés Felipe Cuspoca, Nahid Akthar, Jorge Samuel Leon Magdaleno, Siriluk Rattanabunyong, Chonticha Suwattanasophon, Nathjanan Jongkon, Kiattawee Choowongkomon, Abdul Rajjak Shaikh, Tabarak Malik and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Review
  5. Development of a vaccine construct againstNAR genomics and bioinformatics · 2025
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  15. Multi-epitope Based Peptide Vaccine Candidate AgainstBioinformatics and biology insights · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Mohit ChawlaPhysical Sciences and Engineering Division, Kaust Catalysis Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Andrés Felipe CuspocaGrupo de Investigación en Epidemiología Clínica de Colombia (GRECO), Universidad Pedagógica yTecnológica de Colombia, Tunja, Colombia.
Nahid AktharDepartment of Research and Innovation, STEMskills Research and Education Lab Private Limited, Faridabad, Haryana, India.
Jorge Samuel Leon MagdalenoPhysical Sciences and Engineering Division, Kaust Catalysis Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Siriluk RattanabunyongDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand.
Chonticha SuwattanasophonDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand.
Nathjanan JongkonDepartment of Social and Applied Science, College of Industrial Technology, King Mongkut's University of Technology North Bangkok, Bangkok, Thailand.
Kiattawee ChoowongkomonDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand.
Abdul Rajjak ShaikhDepartment of Research and Innovation, STEMskills Research and Education Lab Private Limited, Faridabad, Haryana, India.
Tabarak MalikDepartment of Biomedical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.
Luigi CavalloPhysical Sciences and Engineering Division, Kaust Catalysis Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Kasetsart University · THKing Abdullah University of Science and Technology · SAJimma University · ETKing Mongkut's University of Technology North Bangkok · THPedagogical and Technological University of Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline infectious peritonitis (FIP) is a grave and frequently lethal ailment instigated by feline coronavirus (FCoV) in wild and domestic feline species. The spike (S) protein of FCoV assumes a critical function in viral ingress and infection, thereby presenting a promising avenue for the development of a vaccine. In this investigation, an immunoinformatics approach was employed to ascertain immunogenic epitopes within the S-protein of FIP and formulate an innovative vaccine candidate. By subjecting the amino acid sequence of the FIP S-protein to computational scrutiny, MHC-I binding T-cell epitopes were predicted, which were subsequently evaluated for their antigenicity, toxicity, and allergenicity through

Indexed as

feline coronavirusfeline infectious peritonitisimmunoinformaticsreverse vaccinologyspike proteinvaccine

Identifiers

PMID38192725
PMCPMC10773687
OpenAlexW4389684212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.