ArticleFrontiers in integrative neuroscience2023
Brain morphological variability between whites and African Americans: the importance of racial identity in brain imaging research.
Article in Frontiers in integrative neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Subregional hypothalamic volumes associate with childhood conduct problems in healthy adults.Brain imaging and behavior · 2026Article
- Brain network features predating early alcohol initiation in adolescence.Translational psychiatry · 2026Article
- The need for cultural sensitivity and epistemic justice in applying neuroscience advances in the Global South.Frontiers in human neuroscience · 2026Article
- Neural propensity for trait rumination in adolescents: A cross-sectional study with Voxel-Based Morphometry.Journal of mood and anxiety disorders · 2025Article
- Structural Covariance Network Properties Predictive of Early Adolescent Alcohol Initiation.bioRxiv : the preprint server for biology · 2025Article
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Abstract
In a segregated society, marked by a historical background of inequalities, there is a consistent under-representation of ethnic and racial minorities in biomedical research, causing disparities in understanding genetic and acquired diseases as well as in the effectiveness of clinical treatments affecting different groups. The repeated inclusion of small and non-representative samples of the population in neuroimaging research has led to generalization bias in the morphological characterization of the human brain. A few brain morphometric studies between Whites and African Americans have reported differences in orbitofrontal volumetry and insula cortical thickness. Nevertheless, these studies are mostly conducted in small samples and populations with cognitive impairment. For this reason, this study aimed to identify brain morphological variability due to racial identity in representative samples. We hypothesized that, in neurotypical young adults, there are differences in brain morphometry between participants with distinct racial identities. We analyzed the Human Connectome Project (HCP) database to test this hypothesis. Brain volumetry, cortical thickness, and cortical surface area measures of participants identified as
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