Evidence map›Paper›PMID 38192326›Full record

ArticleRSC advances2024

Solute-particle separation in microfluidics enhanced by symmetrical convection.

Yurou Yao, Yao Lin, Zerui Wu, Zida Li, Xuemei He, Yun Wu, Zimin Sun, Weiping Ding, Liqun He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yurou YaoDepartment of Thermal Science and Energy Engineering, University of Science and Technology of China Hefei 230026 China heliqun@ustc.edu.cn.
Yao LinDepartment of Thermal Science and Energy Engineering, University of Science and Technology of China Hefei 230026 China heliqun@ustc.edu.cn.
Zerui WuDepartment of Thermal Science and Energy Engineering, University of Science and Technology of China Hefei 230026 China heliqun@ustc.edu.cn.
Zida LiDepartment of Biomedical Engineering, Medical School, Shenzhen University Shenzhen 518060 China.ORCID https://orcid.org/0000-0002-1353-9414
Xuemei HeDepartment of Hematology, The First Affiliated Hospital of University of Science and Technology of China Hefei 230001 China zmsun@ustc.edu.cn.
Yun WuDepartment of Hematology, The First Affiliated Hospital of University of Science and Technology of China Hefei 230001 China zmsun@ustc.edu.cn.
Zimin SunDepartment of Hematology, The First Affiliated Hospital of University of Science and Technology of China Hefei 230001 China zmsun@ustc.edu.cn.
Weiping DingDepartment of Electronic Engineering and Information Science, University of Science and Technology of China Hefei 230026 China wpdings@ustc.edu.cn.ORCID https://orcid.org/0000-0002-3331-1011
Liqun HeDepartment of Thermal Science and Energy Engineering, University of Science and Technology of China Hefei 230026 China heliqun@ustc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The utilization of microfluidic technology for miniaturized and efficient particle sorting holds significant importance in fields such as biology, chemistry, and healthcare. Passive separation methods, achieved by modifying the geometric shapes of microchannels, enable gentle and straightforward enrichment and separation of particles. Building upon previous discussions regarding the effects of column arrays on fluid flow and particle separation within microchips, we introduced a column array structure into an H-shaped microfluidic chip. It was observed that this structure enhanced mass transfer between two fluids while simultaneously intercepting particles within one fluid, satisfying the requirements for particle interception. This enhancement was primarily achieved by transforming the originally single-mode diffusion-based mass transfer into dual-mode diffusion-convection mass transfer. By further optimizing the column array, it was possible to meet the basic requirements of mass transfer and particle interception with fewer microcolumns, thereby reducing device pressure drop and facilitating the realization of parallel and high-throughput microfluidic devices. These findings have enhanced the potential application of microfluidic systems in clinical and chemical engineering domains.

Identifiers

PMID38192326
PMCPMC10772704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.