Evidence map›Paper›PMID 38192160›Full record

Trial reportJournal of rehabilitation medicine2024

Exercise- and education-based prehabilitation before total knee arthroplasty: a pilot study.

Pascale Gränicher, Loes Mulder, Ton Lenssen, Sandro F Fucentese, Jaap Swanenburg, Rob De Bie, Johannes Scherr

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of rehabilitation medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721897 (Effectiveness of a Prehabilitation Program on Clinical, Functional and Psychological Variables in Candidates for Hip or Knee Arthroplasty Surgery.), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721897 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of a Prehabilitation Program on Clinical, Functional and Psychological Variables in Candidates for Hip or Knee Arthroplasty Surgery.

TypeinterventionalSponsorUniversity of JaénRan2025 to 2027Enrolled44ConditionsPrehabilitation, Knee Osteoarthritis, Hip Osteoarthritis, Physical Therapy ModalitiesArmsPrehabilitation Program, Non prehabilitation Program
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pascale GränicherDepartment of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Peter Debyeplein 1, 6229 HA Maastricht, The Netherlands; University Center for Prevention and Sports Medicine, Balgrist University Hospital, University of Zurich, Forchstrasse 319, CH-8008 Zurich, Switzerland. pascale.graenicher@balgrist.ch.
Loes MulderDepartment of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Peter Debyeplein 1, 6229 HA Maastricht, The Netherlands; Maastricht University MUMC+, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Ton LenssenDepartment of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Peter Debyeplein 1, 6229 HA Maastricht, The Netherlands; Maastricht University MUMC+, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Sandro F FucenteseDepartment of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, Forchstrasse 340, CH-8008 Zurich, Switzerland.
Jaap SwanenburgIntegrative Spinal Research ISR, Department of Chiropractic Medicine, Balgrist University Hospital. Forchstrasse 340, 8008, Zurich, Switzerland; UZH Space Hub, Air Force Center - Überlandstrasse 271, 8600 Dübendorf, Switzerland; Institute of Anatomy, Faculty of Medicine, University of Zurich - Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Rob De BieDepartment of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Peter Debyeplein 1, 6229 HA Maastricht, The Netherlands.
Johannes ScherrUniversity Center for Prevention and Sports Medicine, Balgrist University Hospital, University of Zurich, Forchstrasse 319, CH-8008 Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the feasibility and estimates of effects of a supervised exercise- and education-based prehabilitation programme aiming to improve knee functioning compared with usual care in patients awaiting total knee arthroplasty.

designA randomized controlled pilot study. SUBJECTS: Patients receiving primary, unilateral total knee arthroplasty.

methodsPatients randomized to the intervention group participated in a personalized 4-8-week prehabilitation programme before surgery. Feasibility of the intervention and self-reported knee functioning, pain, physical performance and hospital stay were assessed at baseline, immediately preoperatively, 6 and 12 weeks after surgery.

resultsTwenty patients (mean age 72.7±5.95 years) were enrolled in this study. The personalized prehabilitation programme was found to be feasible and safe, with an exercise adherence of 90%. Significant medium interaction effects between groups and over time favouring prehabilitation were reported for the sport subscale of the Knee Osteoarthritis Outcome Score (F(3/54) = 2.895, p = 0.043, η² = 0.139) and Tegner Activity Scale (F(2.2/39.1) = 3.20, p = 0.048, η² = 0.151).

conclusionThe absence of adverse events and high adherence to the programme, coupled with beneficial changes shown in the intervention group, support the conduct of a full-scale trial investigating the effectiveness of prehabilitation.

Indexed as

Arthroplasty, Replacement, KneePreoperative ExerciseAgedExerciseHumansKnee JointPilot Projects

Identifiers

PMID38192160
PMCPMC10859968

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.