Evidence map›Paper›PMID 38192149›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2024

Investigation of The Effect of Metal-based Medicine

Sangita Behera, Mahima Sharma, Roshan Lal, Raj Kumar Regar, Deepika Tripathi, Pankaj Gupta, Godlaveti Vijay Narasimha Kumar, Digvijay Verma, Subhash Kaushik, Anil Khurana

Abstract read
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In one paragraph

Article in Endocrine, metabolic & immune disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sangita BeheraDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Mahima SharmaDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Roshan LalDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Raj Kumar RegarDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Deepika TripathiDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Pankaj GuptaDepartment of Pharmacology, Dr. D.P. Rastogi, Central Council for Research in Homoeopathy (DDPR-CRIH), Sector 24, Noida, Uttar Pradesh, 201301, India.
Godlaveti Vijay Narasimha KumarDepartment of Pharmacology, DAC Regional Research Institute for Homoeopathy, Kolkata, India.
Digvijay VermaDrug Standarsise Unit, Central Council for Research in Homoeopathy, New Delhi, India.
Subhash KaushikDrug Standarsise Unit, Central Council for Research in Homoeopathy, New Delhi, India.
Anil KhuranaDrug Standarsise Unit, Central Council for Research in Homoeopathy, New Delhi, India.
Central Council for Research in Homoeopathy · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn complementary and alternative medicinal systems, the Arsenicum album in ultra-high dilution was used in various therapeutic conditions, considering its effects on the body's immune system, including the COVID-19 pandemic. However, scientific evidence regarding its immunomodulatory effects is insufficient.

objectivesThe current study aimed to investigate the immunomodulatory effects of Arsenicum album in an experimental mouse model. MATERIALS AND

methodsImmunomodulatory activity of potentized dilutions of Arsenicum album

resultsArsenicum album showed significant immunomodulatory activity by increasing primary antibody titer evaluated on day 21 of the treatment in all the dilutions as compared to SRBC and vehicle control group in humoral immune response assay without showing any effect on delayed-type hypersensitivity.

conclusionThe results of this preliminary study indicate that oral administration of Arsenicum album has the potential to augment primary humoral response at all dilutions. Hence, the possibility of using the Arsenicum album could be explored to treat immunological conditions, infections,

Indexed as

ErythrocytesImmunity, HumoralMice, Inbred BALB CAnimalsCOVID-19FemaleHypersensitivity, DelayedImmunizationImmunomodulating AgentsMiceSheepImmunomodulating AgentsArsenicum albumhomoeopathyhumoral immunityimmunization.immunomodulationsheep red blood cells

Identifiers

PMID38192149
OpenAlexW4390783646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.