Evidence map›Paper›PMID 38192138›Full record

ReviewPharmaceutical nanotechnology2025

Overcoming Solubility Challenges: Self-emulsifying Systems for Enhancing the Delivery of Poorly Water-Soluble Antiviral Drugs.

Devesh U Kapoor, Deepak Sharma, Mansi Gaur, Bhupendra G Prajapati, Sontaya Limmatvapirat, Pornsak Sriamornsak

Abstract readReview
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In one paragraph

Review in Pharmaceutical nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Devesh U KapoorDr. Dayaram Patel Pharmacy College, Bardoli, 394601, Gujarat, India.
Deepak SharmaInstitute of Pharmacy, Assam Don Bosco University, Tapesia, Sonapur Gaon, 78240, Assam, India.
Mansi GaurIntegrity Healthcare Solutions Pvt Ltd., Ahmedabad, 380054, Gujarat, India.
Bhupendra G PrajapatiShree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, 384012, India.
Sontaya LimmatvapiratDepartment of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Pornsak SriamornsakDepartment of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary goal of drug formulation is to improve a drug's bioavailability in the body. However, poorly water-soluble drugs present challenging issues related to their solubility and bioavailability factors. Emerging technologies, such as lipid-based drug delivery systems, including micro- or nanoemulsifying drug delivery systems, have become increasingly relevant to address the above challenges. This review presents a thorough overview of self-emulsifying drug delivery systems (SEDDS). It covers the properties, principles, self-emulsification mechanism, formulation strategies, and characterization methods of SEDDS. This review also addresses the delivery of antiviral agents through SEDDS. Moreover, it summarizes the marketed formulations of SEDDS consisting of antiviral agents. This review offers a comprehensive and valuable resource for future perspectives on SEDDS and their potential applications in antiviral drug delivery.

Indexed as

Antiviral AgentsDrug Delivery SystemsAnimalsBiological AvailabilityEmulsionsHumansSolubilityWaterAntiviral AgentsEmulsionsWaterantiviral drug.biopharmaceutical classification systemcosurfactantpharmacokineticsquality target product profileSelf-emulsifying drug delivery systems

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.