ArticleBiophysical journal2024
Anomalous coarsening of coalescing nucleoli in human cells.
Article in Biophysical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- The effect of microgravity and flows on the organization and dynamics of the human genome.Science advances · 2026Article
- Active processes shape and move the genome and nucleoplasm.Current opinion in genetics & development · 2026Review
- Periodic confined cell migration drives partially reversible chromatin reorganization in cancer cell lines.Communications biology · 2026Article
- Mechanobiology of the Nucleolus.Biology of the cell · 2026Review
- Emerging biophysical principles of macromolecular phase separation.Biophysical journal · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
Coarsening is a ubiquitous phenomenon in droplet systems near thermodynamic equilibrium-as an increase in droplet size lowers the system's free energy-however, coarsening of droplets in nonequilibrium systems, such as the cell nucleus, is far from understood. Liquid condensates in the cell nucleus, like nucleoli, form by liquid-liquid phase separation and play a key role in the nuclear organization. In human cells, nucleolar droplets are nucleated at the beginning of the cell cycle and coarsen with time by coalescing with each other. Upon coarsening, human nucleoli exhibit an anomalous volume distribution P(V)∼V
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