Evidence map›Paper›PMID 38191903›Full record

ArticleScientific reports2024

In vitro gastrointestinal gas monitoring with carbon nanotube sensors.

Sahira Vasquez, Martina Aurora Costa Angeli, Andrea Polo, Alice Costantini, Mattia Petrelli, Enrico Avancini, Raffaella Di Cagno, Marco Gobbetti, Andrea Gaiardo, Matteo Valt and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Battery-Free, Stretchable, and Autonomous Smart Packaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Simulator of the Human Intestinal Microbial Ecosystem (SHIMEPharmaceuticals (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sahira VasquezSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy. svasquezbaez@unibz.it.
Martina Aurora Costa AngeliSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Andrea PoloMicro4Food Lab, Faculty of Agricultural, Food, and Environmental Sciences, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Alice CostantiniMicro4Food Lab, Faculty of Agricultural, Food, and Environmental Sciences, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Mattia PetrelliSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Enrico AvanciniSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Raffaella Di CagnoMicro4Food Lab, Faculty of Agricultural, Food, and Environmental Sciences, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Marco GobbettiMicro4Food Lab, Faculty of Agricultural, Food, and Environmental Sciences, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Andrea GaiardoMicro Nano Facility, Bruno Kessler Foundation, 38123, Trento, Italy.
Matteo ValtMicro Nano Facility, Bruno Kessler Foundation, 38123, Trento, Italy.
Paolo LugliSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy.
Luisa PettiSensing Technologies Laboratory (STL), Faculty of Engineering, Free University of Bozen-Bolzano, 39100, Bolzano, Italy. luisa.petti@unibz.it.
Free University of Bozen-Bolzano · ITFondazione Bruno Kessler · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vitro simulators of the human gastrointestinal (GI) tract are remarkable technological platforms for studying the impact of food on the gut microbiota, enabling continuous and real-time monitoring of key biomarkers. However, comprehensive real-time monitoring of gaseous biomarkers in these systems is required with a cost-effective approach, which has been challenging to perform experimentally to date. In this work, we demonstrate the integration and in-line use of carbon nanotube (CNT)-based chemiresitive gas sensors coated with a thin polydimethylsiloxane (PDMS) membrane for the continuous monitoring of gases within the Simulator of the Human Microbial Ecosystem (SHIME). The findings demonstrate the ability of the gas sensor to continuously monitor the different phases of gas production in this harsh, anaerobic, highly humid, and acidic environment for a long exposure time (16 h) without saturation. This establishes our sensor platform as an effective tool for real-time monitoring of gaseous biomarkers in in vitro systems like SHIME.

Indexed as

GasesIntestinesBiomarkersFoodHumansNanotubes, CarbonBiomarkersGasesNanotubes, Carbon

Identifiers

PMID38191903
PMCPMC10774382
OpenAlexW4390674208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.