Evidence map›Paper›PMID 38191885›Full record

ArticleScientific reports2024

Dosimetric characterization of a novel UHDR megavoltage X-ray source for FLASH radiobiological experiments.

Nolan Esplen, Luca Egoriti, Thomas Planche, Stephanie Rädel, Hui-Wen Koay, Brandon Humphries, Xi Ren, Nancy Ford, Cornelia Hoehr, Alexander Gottberg and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nolan EsplenPhysics and Astronomy, University of Victoria, Victoria, V8P 5C2, Canada.
Luca EgoritiTRIUMF, Vancouver, V6T 2A3, Canada.
Thomas PlancheTRIUMF, Vancouver, V6T 2A3, Canada.
Stephanie RädelTRIUMF, Vancouver, V6T 2A3, Canada.
Hui-Wen KoayTRIUMF, Vancouver, V6T 2A3, Canada.
Brandon HumphriesTRIUMF, Vancouver, V6T 2A3, Canada.
Xi RenPhysics and Astronomy, University of British Columbia, Vancouver, V6T 1Z1, Canada.
Nancy FordPhysics and Astronomy, University of British Columbia, Vancouver, V6T 1Z1, Canada.
Cornelia HoehrPhysics and Astronomy, University of Victoria, Victoria, V8P 5C2, Canada.
Alexander GottbergPhysics and Astronomy, University of Victoria, Victoria, V8P 5C2, Canada.
Magdalena Bazalova-CarterPhysics and Astronomy, University of Victoria, Victoria, V8P 5C2, Canada. bazalova@uvic.ca.
TRIUMF · CAUniversity of Victoria · CAUniversity of British Columbia · CA

Funding

Canada Research Chairs CRC-2019-00039Natural Sciences and Engineering Research Council of Canada RGPIN-2021-03516Natural Sciences and Engineering Research Council of Canada RPGIN-2016-03749Social Sciences and Humanities Research Council of Canada NFRFE-2018-00102
6 · The paper itself

Abstract

A first irradiation platform capable of delivering 10 MV X-ray beams at ultra-high dose rates (UHDR) has been developed and characterized for FLASH radiobiological research at TRIUMF. Delivery of both UHDR (FLASH mode) and low dose-rate conventional (CONV mode) irradiations was demonstrated using a common source and experimental setup. Dose rates were calculated using film dosimetry and a non-intercepting beam monitoring device; mean values for a 100 μA pulse (peak) current were nominally 82.6 and 4.40 × 10

Indexed as

BenchmarkingRadiometryAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLRadiographyX-Rays

Identifiers

PMID38191885
PMCPMC10774358
OpenAlexW4390661895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.