Evidence map›Paper›PMID 38191876›Full record

ArticleBulletin of experimental biology and medicine2023

Features of Hemolysin Biosynthesis by Morganella morganii.

L F Minnullina, P S Misheeva, G I Mukhtarova, M R Sharipova, A M Mardanova

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

L F MinnullinaKazan (Volga region) Federal University, Kazan, Republic of Tatarstan, Russia. masaco@mail.ru.
P S MisheevaKazan (Volga region) Federal University, Kazan, Republic of Tatarstan, Russia.
G I MukhtarovaKazan (Volga region) Federal University, Kazan, Republic of Tatarstan, Russia.
M R SharipovaKazan (Volga region) Federal University, Kazan, Republic of Tatarstan, Russia.
A M MardanovaKazan (Volga region) Federal University, Kazan, Republic of Tatarstan, Russia.
Kazan Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the influence of medium composition and aeration on the hemolytic activity of uropathogenic Morganella morganii strain MM 190. The maximum level of hemolysis was observed in LB (59%), DMEM supplemented with fetal bovine serum (62%), and urine (53%) under aeration conditions during the exponential growth phase. The presence of 2% urea in the medium suppressed hemolysin synthesis. Moreover, addition of bacterial culture fluid containing hemolysin to a monolayer of T-24 bladder carcinoma and OKP-GS kidney carcinoma cells led to 25 and 42% cell death, respectively. We found that the maximum expression of the hemolysin gene hlyA was observed in 2-h culture in LB medium, which correlated with the hemolytic activity of the bacteria in this medium and indicated the predominance of the short hlyCA transcript in the cells.

Indexed as

CarcinomaMorganella morganiiAntigens, BacterialHemolysin ProteinsHemolysisHumansAntigens, BacterialHemolysin Proteinscytotoxicitygene expressionMorganella morganiiRTX toxinsuropathogens

Identifiers

PMID38191876
OpenAlexW4390659993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.