Trial reportLasers in medical science2024
Investigation of the efficacy of two different laser types in the treatment of lower lip paresthesia after sagittal split ramus osteotomy.
Trial report in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review.Clinical and experimental dental research · 2025Pooled it
- Single-session extraoral photobiomodulation reduces early postoperative pain but not edema or trismus after impacted mandibular third molar extraction: a randomized controlled trial.Lasers in medical science · 2026Trial
- The Use of Laser Photobiomodulation in the Treatment of Oro-Facial Neurosensory Alterations-A Case Series from a University Clinic.Healthcare (Basel, Switzerland) · 2026Article
- Multimodal physiotherapeutic management of postoperative complications in orthognathic surgery: A literature review and institutional protocol proposal.Medicina oral, patologia oral y cirugia bucal · 2026Review
- Histopathological examination of the effects of two different laser types on the osteochondral defect created in the rabbit temporomandibular joint.Scientific reports · 2026Article
- The effect of photobiomodulation therapy on neurosensory recovery of infra-alveolar nerve following iatrogenic trauma: A literature review.Journal of dental sciences · 2026Article
- Evaluation, prevention, and treatment of inferior alveolar nerve injury in bilateral sagittal split mandibular osteotomy.Maxillofacial plastic and reconstructive surgery · 2025Review
- Investigation of the effect of photobiomodulation therapy with different wavelengths on nerve regeneration: an experimental study.BMC oral health · 2025Article
- Comparison of the effectiveness of the new generation dual wavelength laser with the conventional laser type in treating rabbit model temporomandibular joint osteoarthritis.BMC oral health · 2025Article
- Photobiomodulation Therapy for Neurosensory Disturbances in Orthognathic Surgery Patients: A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Efficacy of Blood Products and Photobiomodulation Therapy for Neurosensory Recovery in Patients With Inferior Alveolar Nerve Injury Following Orthognathic Surgery: A Systematic Review Study.Journal of lasers in medical sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Orthognathic surgery involves invasive and major surgical procedures commonly used to correct maxillofacial deformities. Bilateral sagittal split ramus osteotomy (BSSO) is often used to treat dentofacial anomalies related to the mandible, but it can result in various complications, the most common of which is inferior alveolar nerve damage. Nerve damage-induced paresthesia of the lower lip significantly affects patient comfort. Medical treatments such as steroids and vitamin B, low-level laser therapy (LLLT), and platelet-rich fibrin (PRF) can be used as supportive therapies for nerve regeneration after damage. This study aimed to investigate the effectiveness of two different types of lasers in treating lower lip paresthesia after BSSO. This clinical trial was a controlled, single-center, prospective, single-blind, randomized study. Thirty patients were included in the study and randomly assigned to three groups: Group I (laser GRR, n = 10) received transcutaneous and transmucosal GRR laser treatment, Group II (Epic10 laser, n = 10) received transmucosal and transcutaneous Epic10 laser treatment, and Group III (vitamin B, n = 10) received B-complex vitamin tablets orally once a day. Two-point and brush tests were performed six times at specific intervals, and a visual analog scale was used to evaluate pain and sensitivity. Both vitamin B and laser therapies accelerated nerve regeneration. The contribution of the laser groups to the healing rate was better than that of the vitamin B group. Although there was no statistically significant difference between the two laser groups, clinical observations indicated better results in the GRR laser group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.