Evidence map›Paper›PMID 38191432›Full record

ArticleBMC oral health2024

BML-111 inhibit H

Yao Xu, Yi Chu, Wanrong Yang, Kefei Chu, Sihui Li, Ling Guo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Frontiers in microbiology · 2026
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yao XuLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China.
Yi ChuLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China.
Wanrong YangLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China.
Kefei ChuLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China.
Sihui LiLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China.
Ling GuoLuzhou Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, China. 372083745@qq.com.
Southwest Medical University · CNFourth People's Hospital of Sichuan Province · CN

Funding

Southwest Medical University 2021ZKZD008
6 · The paper itself

Abstract

backgroundPeriodontitis is a common and harmful chronic inflammatory oral disease, characterized by the destruction of periodontal soft and hard tissues. The NLRP3 inflammasome-related pyroptosis and human periodontal ligament fibroblasts (hPDLFs) osteogenic dysfunction are involved in its pathogenesis. Studies have shown that lipoxin A4 is an endogenous anti-inflammatory mediator and BML-111 is a lipoxin A4 analog, which was found to have potent and durable anti-inflammatory effects in inflammatory diseases, but the mechanism remains unclear. The purpose of this study was to investigate whether BML-111 inhibits H

methodsThe oxidative stress model was established with H

resultsBML-111 can alleviate the impaired cell proliferation viability induced by H

conclusionThe results of this study confirmed the beneficial effects of BML-111 on H

Indexed as

PeriodontitisPyroptosisAnti-Inflammatory AgentsFibroblastsHeptanoic AcidsHumansHydrogen PeroxideInflammasomesNF-E2-Related Factor 2NLR Family, Pyrin Domain-Containing 3 ProteinOsteogenesisPeriodontal Ligament5(S),6(R)-7-trihydroxyheptanoic acid, methyl esterAnti-Inflammatory AgentsHeptanoic AcidsHydrogen PeroxideInflammasomesNF-E2-Related Factor 2NLR Family, Pyrin Domain-Containing 3 ProteinLipoxin A4 analogNLRP3Nrf2PyroptosisReactive oxygen species

Identifiers

PMID38191432
PMCPMC10773113
OpenAlexW4390669318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.