Trial reportBMC public health2024
Addressing help-seeking, stigma and risk factors for suicidality in secondary schools: short-term and mid-term effects of the HEYLiFE suicide prevention program in a randomized controlled trial.
Trial report in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Gatekeeper training for suicide prevention: a systematic review and meta-analysis of randomized controlled trials.BMC public health · 2025Pooled it
- Trial
- Gatekeepers or Roadblocks? Longitudinal Associations Between Chinese Homeroom Teachers' Response Profiles Regarding Student Self-Harm and Students' Help-Seeking Intentions.Journal of youth and adolescence · 2026Article
- Suicide risk assessment: clinical implications of the unpredictability of suicidal behavior.Frontiers in psychiatry · 2026Article
- Suicide prevention program on suicidal behaviors and mental wellbeing among school aged adolescents: a scoping review.Frontiers in public health · 2025Article
- Suicide prevention for international students: A single-arm mixed methods evaluation of the LivingWorks safeTALK program in Australia.Global mental health (Cambridge, England) · 2025Article
- Behind the data: Reflections from conducting school-based suicide prevention research with young people in the United Kingdom.PLOS mental health · 2025Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSuicidal ideation and suicide attempts present a serious public health concern among adolescents and young adults. School-based suicide prevention programs are a key tool for addressing this problem. However, more research is necessary to assess their effectiveness, acceptability, and safety. In response, the HEYLiFE suicide prevention program was developed to enhance help-seeking, reduce stigma towards suicidal peers and diminish risk factors for suicidality. This article presents the evaluation findings of the HEYLiFE program in German secondary schools.
methodsWe conducted a randomized-controlled trial measuring short-term pre-post within-group effects in the intervention group only and mid-term effects at 6-months-follow-up compared to a waitlist-control group. Schools were assigned randomly to the intervention or control group (no blinding). We recruited students ≥12 years of age. Primary outcomes were knowledge about suicidality, attitudes towards suicidality, stigma towards a suicidal peer, help-seeking intentions and behaviours, risk factors for suicidality. The data was analysed with linear mixed models and generalized linear mixed models.
resultsA total of N = 745 students participated (n = 353 intervention group, n = 392 control group). We observed favourable short-term effects on knowledge, attitudes towards suicidality and fear towards a suicidal peer. Unexpectedly, the program also led to an increase in desire for social distance and a decrease in prosocial emotions towards a suicidal peer. The mid-term effects of the program were exclusively favourable, resulting in enhanced attitudes towards help-seeking while protecting from a sharper rise in risk-factors for suicidality and from an increase in social distance. The program had more favourable effects on females and on students aged >13 years. The program was well-received by the students, and no serious adverse events were reported.
conclusionsThese findings demonstrate the effectiveness of the HEYLiFE universal suicide prevention program in addressing variables associated with suicidal ideation and suicide attempts among adolescents on the mid-term. The short-term negative effects on stigma and more negative effects on males should be addressed in the future. Future evaluation studies should examine its effects on suicidality and its effectiveness within populations at high risk.
trial registrationThe study was preregistered in the German Clinical Trials Register (registration number: DRKS00017045; registration date: 02/04/2019).
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