ArticleBMC infectious diseases2024
Disseminated Talaromyces marneffei infection associated with haemophagocytic syndrome in an HIV-negative patient in northern China: a case report.
Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Multiple recurrences of Talaromyces marneffei infection with HLH in an HIV-negative patient: a case report.BMC infectious diseases · 2026Article
- Epidemiology and factors associated with Talaromyces marneffei detection in the mainland of China, 2022-2024: a cross-sectional study of hospitalized patients.BMC public health · 2026Article
- Challenges in Diagnosis and Treatment of HIV-Negative Host PulmonaryInfection and drug resistance · 2026Article
- Advanced HIV Presenting With Pancytopenia and HLH-Like Hyperinflammation Secondary to Disseminated Talaromycosis: A Case Report.Case reports in infectious diseases · 2026Article
- Pulmonary talaromycosis leads to respiratory failure in an HIV-negative patient in Shandong Province: case report.BMC infectious diseases · 2025Article
- Fungal-Induced Hemophagocytic Lymphohistiocytosis: A Literature Review in Non-HIV Populations.Journal of fungi (Basel, Switzerland) · 2025Review
- The role of mNGS in the diagnosis of talaromycosis and case series.BMC infectious diseases · 2025Article
- An overview of rapid non-culture-based techniques in various clinical specimens for the laboratory diagnosis ofFrontiers in cellular and infection microbiology · 2025Review
- InvasiveInfection and drug resistance · 2025Article
- Generalized cutaneous talaromycosis (Penicilliosis) in an immunocompetent individual.JAAD case reports · 2024Article
- HIV-Negative Case ofInfection and drug resistance · 2024Article
- The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies.Therapeutic advances in infectious diseaseReview
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Abstract
backgroundTalaromyces marneffei is endemic to eastern India, Southeast Asia, and Guangdong and Guangxi provinces in China. It is common in immunocompromised individuals, especially in HIV-infected patients. CASE PRESENTATION: A 66-year-old male who had a history of hypertension and resided in Shandong Province (Northern China) was admitted for recurrent fever for one month. The patient had recurrent fever, multiple lymphadenopathies, hepatosplenomegaly, a back rash, and a progressive decrease in white blood cells and platelets. Talaromyces marneffei was isolated from peripheral blood and bone marrow after admission, and suspected fungal cells were found via lymph node pathology. The patient's infection secondary to haemophagocytic syndrome continued to worsen despite antifungal, anti-inflammatory, and symptomatic treatment, leading to death due to multiple-organ failure.
conclusionAlthough rare, infection due to Talaromyces marneffei in HIV-negative patients has been increasing in recent years, and we should be vigilant about "new" infections in nonendemic areas.
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