Evidence map›Paper›PMID 38191283›Full record

ArticleBMC genomics2024

mosGILT controls innate immunity and germ cell development in Anopheles gambiae.

Gunjan Arora, Xiaotian Tang, Yingjun Cui, Jing Yang, Yu-Min Chuang, Jayadev Joshi, Andaleeb Sajid, Yuemei Dong, Peter Cresswell, George Dimopoulos and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Article
  6. Comparative immunological roles of TEP1 inFrontiers in immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Gunjan Arora *Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA. arorag1983@gmail.com.
Xiaotian Tang *Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA.
Yingjun CuiSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA.
Jing YangSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA.
Yu-Min ChuangSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA.
Jayadev JoshiGenomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio, 44195, USA.
Andaleeb SajidSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA.
Yuemei DongW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, 21205, USA.
Peter CresswellDepartment of Immunobiology, Yale School of Medicine, New Haven, Connecticut, 06510, USA.
George DimopoulosW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, 21205, USA.
Erol FikrigSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, 06520, USA. erol.fikrig@yale.edu.
Yale University · USJohns Hopkins University · USCleveland Clinic · USLanzhou University Second Hospital · CN

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Regional Biocontainment LaboratoryUC6AI058615 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI KORNEGAY, JOE N · 2003 to 2006
$13.4M
AgTRIO, a protein in mosquito saliva, influences Plasmodium sporozoite infectionR21AI142708 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL · 2020 to 2021
$461k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R21 AI142708NIAID NIH HHS UC6 AI058615NIH HHS AI142708, and AI58615
6 · The paper itself

Abstract

Gene-edited mosquitoes lacking a gamma-interferon-inducible lysosomal thiol reductase-like protein, namely (mosGILT

Indexed as

AnophelesAnimalsCell DifferentiationGerm CellsImmunity, InnateMosquito Vectors20-HydroxyecdysoneAnophelesFat bodyGenomicsGILTImmunityMalariaMetabolismmosGILTMosquitoMosquito ReproductionMosuito ImmunityOvarian DevelopmentZPG

Identifiers

PMID38191283
PMCPMC10775533
OpenAlexW4390726975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.