Evidence map›Paper›PMID 38190959›Full record

ArticleThe American journal of medicine2024

Racial/Ethnic Disparities in Aortic Valve Replacement Among Medicare Beneficiaries in the United States, 2012-2019.

Aakriti Gupta, Makoto Mori, Yun Wang, Shubhadarshini G Pawar, Torsten Vahl, Tamim Nazif, Oyere Onuma, Celina M Yong, Rahul Sharma, Ajay J Kirtane and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. How Sex and Race/Ethnicity Influence Interventional Cardiology Outcomes: What Do We Know?Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Racial Disparities Among Patients Undergoing Balloon-Expandable Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Aakriti GuptaDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif; Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Conn.
Makoto MoriCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Conn; Division of Cardiac Surgery, Yale School of Medicine, New Haven, Conn.
Yun WangCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Conn; Division of Cardiology, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.
Shubhadarshini G PawarDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Torsten VahlDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Tamim NazifDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Oyere OnumaDivision of Cardiology, Department of Medicine, Yale University School of Medicine, New Haven, Conn.
Celina M YongDivision of Cardiology, Department of Medicine, Stanford Medical Center, California and Veterans Affairs Palo Alto Healthcare System, Palo Alto.
Rahul SharmaDivision of Cardiology, Department of Medicine, Stanford Medical Center, California and Veterans Affairs Palo Alto Healthcare System, Palo Alto.
Ajay J KirtaneDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
John K ForrestDepartment of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT.
Isaac GeorgeCardiothoracic Surgery, Columbia University Irving Medical Center, New York, NY.
Susheel KodaliDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Joanna ChikweDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Arnar GeirssonDivision of Cardiac Surgery, Yale School of Medicine, New Haven, Conn.
Raj MakkarDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Martin B LeonDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Conn; Department of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT; Department of Health Policy and Management, Yale School of Public Health, New Haven, Conn. Electronic address: harlan.krumholz@yale.edu.
Columbia University Irving Medical Center · USCedars-Sinai Medical Center · USYale New Haven Hospital · USYale University · USVA Palo Alto Health Care System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
POSTDOCTORAL TRAINING IN CARDIOVASCULAR DISEASET32HL007854 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marwah Abdalla, Michael Argenziano · 1996 to 2026
$14.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL007854
6 · The paper itself

Abstract

purposeThere are concerns that transcatheter or surgical aortic valve replacement (TAVR/SAVR) procedures are preferentially available to White patients. Our objective was to examine differences in utilization of aortic valve replacement and outcomes by race/ethnicity in the US for patients with aortic stenosis.

methodsWe performed a serial cross-sectional cohort study of 299,976 Medicare beneficiaries hospitalized with principal diagnosis of aortic stenosis between 2012 and 2019 stratified by self-reported race/ethnicity (Black, Hispanic, Asian, Native American, and White). Outcomes included aortic valve replacement rates within 6 months of index hospitalization and associated procedural outcomes, including 30-day readmission, 30-day and 1-year mortality.

resultsWithin 6 months of an index admission for aortic stenosis, 86.8% (122,457 SAVR; 138,026 TAVR) patients underwent aortic valve replacement. Overall, compared with White people, Black (HR 0.87 [0.85-0.89]), Hispanic (0.92 [0.88-0.96]), and Asian (0.95 [0.91-0.99]) people were less likely to receive aortic valve replacement. Among patients who were admitted emergently/urgently, White patients (41.1%, 95% CI, 40.7-41.4) had a significantly higher aortic valve replacement rate compared with Black (29.6%, 95% CI, 28.3-30.9), Hispanic (36.6%, 95% CI, 34.0-39.3), and Asian patients (35.4%, 95% CI, 32.3-38.9). Aortic valve replacement rates increased annually for all race/ethnicities. There were no significant differences in 30-day or 1-year mortality by race/ethnicity.

conclusionsAortic valve replacement rates within 6 months of aortic stenosis admission are lower for Black, Hispanic, and Asian people compared to White people. These race-related differences in aortic stenosis treatment reflect complex issues in diagnosis and management, warranting a comprehensive reassessment of the entire care spectrum for disadvantaged populations.

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementAgedAortic ValveCross-Sectional StudiesHumansMedicareRisk FactorsTreatment OutcomeUnited StatesAortic valve replacementDisparitiesMedicareUnited states

Identifiers

PMID38190959
PMCPMC11019903
OpenAlexW4390639230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.