Evidence map›Paper›PMID 38190887›Full record

ArticleThe journal of allergy and clinical immunology. In practice2024

Food Allergy Reaction Severity and Management in a Diverse Population.

Samantha Kay-Green, Neil Thivalapill, Lucy Bilaver, Jialing Jiang, Amal Assa'ad, Susan Fox, Hemant Sharma, Mahboobeh Mahdavinia, Linda Herbert, Christopher Warren and 1 more

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Health inequities in pediatric anaphylaxis: A policy framework and call to action for equitable care from SIAIP allergy prevention commission.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Review
  2. Implementation of early peanut introduction among providers in a southern US state.The journal of allergy and clinical immunology. Global · 2026
    Article
  3. Addressing Health Equity in Food Allergy.The journal of allergy and clinical immunology. In practice · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Samantha Kay-GreenInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Neil ThivalapillInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Lucy BilaverInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Jialing JiangInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Amal Assa'adDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Susan FoxDivision of Allergy and Immunology, Department of Medicine and Department of Pediatrics, Rush University Medical Center, Chicago, Ill.
Hemant SharmaDivision of Allergy and Immunology, Children's National Health Systems, Washington, DC.
Mahboobeh MahdaviniaDivision of Allergy and Immunology, Department of Medicine and Department of Pediatrics, Rush University Medical Center, Chicago, Ill.
Linda HerbertChildren's National Medical Center, Washington, DC; George Washington University School of Medicine, Washington, DC.
Christopher WarrenInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Ruchi GuptaInstitute for Public Health and Medicine, Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill; Department of General Academic Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill. Electronic address: r-gupta@northwestern.edu.
Northwestern University · USChildren's National · USRush University Medical Center · USCincinnati Children's Hospital Medical Center · US

Funding

FORWARD Supplement Standardizing EHR Data CollectionR01AI130348 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Ruchi S Gupta · 2017 to 2026
$10.9M
NIAID NIH HHS R01 AI130348
6 · The paper itself

Abstract

backgroundDefinitive treatment for food allergy reactions including anaphylaxis varies widely by reaction severity and socioeconomic status, but little data exist to characterize the relationship between severity, management, and race and ethnicity.

objectiveTo analyze the differences in reaction severity, epinephrine use, and emergency room (ER) use by race and ethnicity in a large, diverse, food-allergic cohort.

methodsWe analyzed intake data from participants in the Food Allergy Outcomes Related to White and African-American Racial Differences cohort on the history of food allergy reactions, severity of the reactions, and management associated with each reaction. We used descriptive statistics as well as mixed-effects logistic and Poisson models to describe the differences in reaction severity, ER visits, and total lifetime epinephrine use by race and ethnicity.

resultsA total of 784 children were included in the analysis: 425 (54.2%) were non-Hispanic White, 282 (36.0%) were non-Hispanic Black, and 77 (9.8%) were Hispanic/Latino. Non-Hispanic Black children had increased odds of more severe reactions (odds ratio, 1.7; 95% CI, 1.2-2.3) and higher odds of going to the ER (odds ratio, 2.8; 95% CI, 1.4-5.4). Both non-Hispanic Black (incidence rate ratio, 0.4; 95% CI, 0.3-0.5) and Hispanic/Latino (incidence rate ratio, 0.3; 95% CI, 0.2-0.5) children had lower rates of total lifetime epinephrine use.

conclusionsThere are significant disparities in the severity and treatment of food allergy reactions by race and ethnicity, resulting in increased ER use and decreased total lifetime epinephrine use. Equipping parents with resources and tools on management of food allergy reactions may result in decreased disparity in access to definitive care.

Indexed as

Food HypersensitivityHispanic or LatinoBlack or African AmericanChildEpinephrineEthnicityHumansWhiteEpinephrineAllergic reactionFood allergyHealth disparities

Identifiers

PMID38190887
PMCPMC10939854
OpenAlexW4390640732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.