Evidence map›Paper›PMID 38190731›Full record

ArticleACS sensors2024

A Low-Cost, Tabletop LOD-EPR System for Nondestructive Quantification of Iron Oxide Nanoparticles in Tissues.

Saurin Kantesaria, Xueyan Tang, Steven Suddarth, Jacqueline Pasek-Allen, Bat-Erdene Namsrai, Arjun Goswitz, Mikaela Hintz, John Bischof, Michael Garwood

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Saurin KantesariaCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-5495-836X
Xueyan TangCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Steven SuddarthCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Jacqueline Pasek-AllenDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Bat-Erdene NamsraiDepartment of Surgery, University of Minnesota, 420 Delaware Street SE, Minneapolis, Minnesota 55455, United States.
Arjun GoswitzDepartment of Mechanical Engineering, University of Minnesota, 111 Church St. SE, Minneapolis, Minnesota 55455, United States.
Mikaela HintzDepartment of Mechanical Engineering, University of Minnesota, 111 Church St. SE, Minneapolis, Minnesota 55455, United States.
John BischofDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-6726-7111
Michael GarwoodCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.
University of Minnesota · US

Funding

Quantification of Iron Oxide Nanoparticles in Cryopreserved Kidneys with Longitudinally Detected Electron Paramagnetic ResonanceF30DK137445 · NIDDK · UNIVERSITY OF MINNESOTA · PI Saurin Kantesaria · 2024 to 2026
$128k
NIDDK NIH HHS F30 DK137445
6 · The paper itself

Abstract

Iron oxide nanoparticles (IONPs) have wide utility in applications from drug delivery to the rewarming of cryopreserved tissues. Due to the complex behavior of IONPs (e.g., uneven particle distribution and aggregation), further developments and clinical translation can be accelerated by having access to a noninvasive method for tissue IONP quantification. Currently, there is no low-cost method to nondestructively track IONPs in tissues across a wide range of concentrations. This work describes the performance of a low-cost, tabletop, longitudinally detected electron paramagnetic resonance (LOD-EPR) system to address this issue in the field of cryopreservation, which utilizes IONPs for rewarming of rat kidneys. A low-cost LOD-EPR system is realized via simultaneous transmit and receive using MHz continuous-wave transverse excitation with kHz modulation, which is longitudinally detected at the modulation frequency to provide both geometric and frequency isolation. The accuracy of LOD-EPR for IONP quantification is compared with NMR relaxometry. Solution measurements show excellent linearity (

Indexed as

Magnetic Resonance ImagingWaterElectron Spin Resonance SpectroscopyMagnetic Iron Oxide NanoparticlesMagnetic Resonance SpectroscopyWatercryopreservationelectron paramagnetic resonanceiron oxide nanoparticleslow frequencynuclear magnetic resonance

Identifiers

PMID38190731
PMCPMC12145166
OpenAlexW4390661160

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.