ArticleAmerican journal of respiratory and critical care medicine2024
Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes.
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Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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44citing papers in PubMed, 1 pooled it
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A consensus immune dysregulation framework for sepsis and critical illnesses.Nature medicine · 2025Guideline
- Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.The Journal of clinical investigation · 2026Trial
- Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing.bioRxiv : the preprint server for biology · 2026Article
- The Acute Respiratory Distress Syndrome (ARDS): epidemiology, etiology, molecular mechanisms, diagnosis and therapeutic strategies.Molecular biomedicine · 2026Review
- The leaky gut and microbiome in critical illness: emerging insights into microbial "translocation".Current opinion in critical care · 2026Review
- ERS Congress 2025: highlights from the Respiratory Intensive Care Assembly.ERJ open research · 2026Article
- The bug, the burden, and the biology: beyond host-centric phenotyping in sepsis.The Journal of clinical investigation · 2026Article
- Pathogen characteristics are key determinants of distinct host response phenotypes of sepsis.The Journal of clinical investigation · 2026Observational
- Article
- Elevated serum peroxiredoxin 1 is a biomarker of multiorgan failure in ARDS.BMJ open respiratory research · 2026Article
- Microbial lung-to-blood translocation associates with systemic inflammation in severe pneumonia: evidence from paired plasma and lower respiratory tract metagenomics.Intensive care medicine experimental · 2026Article
- Data-driven spatial-temporal framework for exploring the heterogeneity and temporality of sepsis.Chinese medical journal · 2026Review
- Artificial Intelligence- and Machine Learning-Assisted Subphenotyping for Personalized Immunotherapy in Sepsis.Journal of personalized medicine · 2026Review
- Genomic and integrative based progression biomarker discovery in adult sepsis: toward clinical stratification and precision medicine.Annals of intensive care · 2026Review
- Blood mNGS-Detected Epstein-Barr Virus in ICU Patients with Pneumonia: Associations with Disease Severity Markers and Inflammatory Burden.Infection and drug resistance · 2026Article
- The immunology of sepsis: translating new insights into clinical practice.Nature reviews. Nephrology · 2026Review
- Host-Microbe Multiomic Profiling Predicts Mortality in Sepsis.American journal of respiratory and critical care medicine · 2026Article
- Hyper-inflammation and immunosuppression: redefining sepsis therapy using modern approaches.Frontiers in pharmacology · 2026Review
- Metagenomic Cell-free DNA Sequencing for Treatment Monitoring in Sepsis.Research square · 2025Article
- Acute Respiratory Distress Syndrome Molecular Phenotypes Have Distinct Lower Respiratory Tract Transcriptomes.American journal of respiratory and critical care medicine · 2025Article
Corrections and comments
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Authors and funding
19 authors.
Lucile P A NeytonDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.ORCID 0000-0003-1273-2228
Pratik SinhaDepartment of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri.
Aartik SarmaDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Eran MickDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.ORCID 0000-0002-7299-808X
Katrina KalantarChan Zuckerberg Initiative, Redwood City, California.
Stephanie ChenDepartment of Medicine.
Nelson WuDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Kevin DelucchiDepartment of Psychiatry and Behavioral Sciences.
Hanjing ZhuoDepartment of Anesthesiology, and.
Lieuwe D J BosDepartment of Intensive Care and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, the Netherlands.
Alejandra JaureguiDepartment of Medicine.
Antonio GomezDepartment of Medicine.
Carolyn M HendricksonDepartment of Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California; and.
Kirsten N KangelarisDepartment of Medicine.
Aleksandra LeligdowiczDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-6055-4644
Kathleen D LiuDepartment of Anesthesiology, and.
Michael A MatthayCardiovascular Research Institute, University of California, San Francisco, San Francisco, California.
Charles R LangelierDivision of Infectious Diseases.
Carolyn S CalfeeDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Funding
Precision Medicine in the Acute Respiratory Distress SyndromeR35HL140026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CALFEE, CAROLYN · 2018 to 2024
$6.8MPrecision Medicine in Sepsis with Critical IllnessR35GM142992 · NIGMS · WASHINGTON UNIVERSITY · PI Pratik Sinha · 2021 to 2026
$2.4MIntegrated Host/Microbe Metagenomics to Improve Lower Respiratory Tract Infection Diagnosis in Critically Ill ChildrenR01HL155418 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANGELIER, CHARLES · 2021 to 2024
$1.6MEvolution and resolution of ARDS molecular phenotypesK23HL163491 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Aartik Sarma · 2023 to 2026
$750kProfiling the Lung Transcriptome for Precision Diagnosis of Respiratory Infections using Host/Pathogen Metagenomic SequencingK23HL138461 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANGELIER, CHARLES · 2018 to 2021
$718kNHLBI NIH HHS K23 HL138461NHLBI NIH HHS K23 HL163491NHLBI NIH HHS R01 HL155418NHLBI NIH HHS R35 HL140026NIGMS NIH HHS R35 GM142992NIH HHS 1R35 HL140026
Abstract
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Indexed as
Respiratory Distress SyndromeSepsisCritical IllnessHumansPhenotypeProspective Studiespathogensphenotypessepsistranscriptomics
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.