Evidence map›Paper›PMID 38190609›Full record

ArticleBiomacromolecules2024

Protein-Rich Rafts in Hybrid Polymer/Lipid Giant Unilamellar Vesicles.

Nika Otrin, Lado Otrin, Claudia Bednarz, Toni K Träger, Farzad Hamdi, Panagiotis L Kastritis, Ivan Ivanov, Kai Sundmacher

Open access · hybridAbstract read
In one paragraph

Article in Biomacromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Nika OtrinProcess Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.ORCID 0000-0002-0792-5466
Lado OtrinProcess Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.ORCID 0000-0001-5862-456X
Claudia BednarzProcess Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.
Toni K TrägerInterdisciplinary Research Center HALOmem and Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Biozentrum, 06120 Halle/Saale, Germany.
Farzad HamdiInterdisciplinary Research Center HALOmem and Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Biozentrum, 06120 Halle/Saale, Germany.
Panagiotis L KastritisInterdisciplinary Research Center HALOmem and Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Biozentrum, 06120 Halle/Saale, Germany.
Ivan IvanovProcess Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.ORCID 0000-0002-4675-5287
Kai SundmacherProcess Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.ORCID 0000-0003-3251-0593
Max Planck Institute for Dynamics of Complex Technical Systems · DEMartin Luther University Halle-Wittenberg · DENational Hellenic Research Foundation · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considerable attention has been dedicated to lipid rafts due to their importance in numerous cell functions such as membrane trafficking, polarization, and signaling. Next to studies in living cells, artificial micrometer-sized vesicles with a minimal set of components are established as a major tool to understand the phase separation dynamics and their intimate interplay with membrane proteins. In parallel, mixtures of phospholipids and certain amphiphilic polymers simultaneously offer an interface for proteins and mimic this segregation behavior, presenting a tangible synthetic alternative for fundamental studies and bottom-up design of cellular mimics. However, the simultaneous insertion of complex and sensitive membrane proteins is experimentally challenging and thus far has been largely limited to natural lipids. Here, we present the co-reconstitution of the proton pump

Indexed as

PolymersUnilamellar LiposomesAdenosine TriphosphateMembrane MicrodomainsMembrane ProteinsPhospholipidsAdenosine TriphosphateMembrane ProteinsPhospholipidsPolymersUnilamellar Liposomes

Identifiers

PMID38190609
PMCPMC10865357
OpenAlexW4390660904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.