Evidence map›Paper›PMID 38190543›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Rapid single-particle chemical imaging of nanoplastics by SRS microscopy.

Naixin Qian, Xin Gao, Xiaoqi Lang, Huiping Deng, Teodora Maria Bratu, Qixuan Chen, Phoebe Stapleton, Beizhan Yan, Wei Min

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Microplastics in the Female Genital Tract and Fetoplacental Continuum: A Lesion-Based Framework for Pathophysiological Interpretation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  11. Microplastics and Nanoplastics in Food: Dietary Toxicology Beyond Particle Counts.Comprehensive reviews in food science and food safety · 2026
    Review
  12. Article
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Naixin QianDepartment of Chemistry, Columbia University, New York, NY 10027.ORCID 0000-0001-6433-063X
Xin GaoDepartment of Chemistry, Columbia University, New York, NY 10027.ORCID 0000-0002-0911-3656
Xiaoqi LangDepartment of Chemistry, Columbia University, New York, NY 10027.
Huiping DengLamont-Doherty Earth Observatory of Columbia University, Palisades, NY 10964.
Teodora Maria BratuLamont-Doherty Earth Observatory of Columbia University, Palisades, NY 10964.
Qixuan ChenDepartment of Biostatistics, Columbia University Mailman School of Public Health, New York, NY 10032.
Phoebe StapletonDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, New Brunswick, NJ 08854.ORCID 0000-0003-3049-4868
Beizhan YanLamont-Doherty Earth Observatory of Columbia University, Palisades, NY 10964.ORCID 0000-0002-1321-779X
Wei MinDepartment of Chemistry, Columbia University, New York, NY 10027.ORCID 0000-0003-2570-3557

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS P30 ES009089
6 · The paper itself

Abstract

Plastics are now omnipresent in our daily lives. The existence of microplastics (1 µm to 5 mm in length) and possibly even nanoplastics (<1 μm) has recently raised health concerns. In particular, nanoplastics are believed to be more toxic since their smaller size renders them much more amenable, compared to microplastics, to enter the human body. However, detecting nanoplastics imposes tremendous analytical challenges on both the nano-level sensitivity and the plastic-identifying specificity, leading to a knowledge gap in this mysterious nanoworld surrounding us. To address these challenges, we developed a hyperspectral stimulated Raman scattering (SRS) imaging platform with an automated plastic identification algorithm that allows micro-nano plastic analysis at the single-particle level with high chemical specificity and throughput. We first validated the sensitivity enhancement of the narrow band of SRS to enable high-speed single nanoplastic detection below 100 nm. We then devised a data-driven spectral matching algorithm to address spectral identification challenges imposed by sensitive narrow-band hyperspectral imaging and achieve robust determination of common plastic polymers. With the established technique, we studied the micro-nano plastics from bottled water as a model system. We successfully detected and identified nanoplastics from major plastic types. Micro-nano plastics concentrations were estimated to be about 2.4 ± 1.3 × 10

Indexed as

Drinking WaterMicroscopyAlgorithmsHumansMicroplasticsPlasticsDrinking WaterMicroplasticsPlasticsnanoplasticsoptical microscopyRaman imagingsingle particle analysisStimulated Raman Scattering

Identifiers

PMID38190543
PMCPMC10801917

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.