Evidence map›Paper›PMID 38190454›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association2024

Predictors of survival among patients with chronic hepatitis C at a tertiary care center in Oman.

Halima H Al-Shuaili, Said A Al-Busafi, Khalid Al-Naamani, Zakariya Al-Naamani

Open access · diamondAbstract read
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Halima H Al-ShuailiDepartment of Medicine, Ibri Hospital, Ibri, Oman.
Said A Al-BusafiDepartment of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Khalid Al-NaamaniDepartment of Medicine, Armed Forces Hospital, Muscat, Oman.
Zakariya Al-NaamaniDepartment of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
College of Applied Sciences- Ibri · OMRoyal Hospital · OMSultan Qaboos University · OMSultan Qaboos University Hospital · OM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic hepatitis C (CHC) is a leading cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide. This study aimed to determine rates and predictors of survival among Omani patients with CHC at a tertiary hospital in Muscat, Oman.

methodsThis ambidirectional cohort study included all CHC patients who presented to the Sultan Qaboos University Hospital between January 2009 and December 2017. Baseline demographic, clinical, laboratory, and radiological data were analyzed. Patients were followed-up until death or the endpoint of the study (April 2022) to determine survival and associations with other parameters.

resultsA total of 702 CHC patients were included, of which 398 (56.7%) were under 50 years of age and 477 (67.9%) were male. Overall, 180 patients (25.6%) died by the study endpoint. The mean duration of follow-up was 93.3 ± 48.0 months. The 5-year survival rate was estimated to be 80.5%, while the 10-year survival was 73%. Sustained virological response and the absence of diabetes mellitus, chronic kidney disease, HCC, or other malignancies were associated with significantly better overall survival. The 3- and 5-year survival rate of patients with hepatitis C virus (HCV)-related HCC was 46.5% and 27.6%, respectively, with a median survival of 29.5 months. Co-infection with hepatitis B was associated with poor survival among this subgroup; conversely, early HCV screening and the presence of a single HCC lesion were associated with better overall survival.

conclusionsNational policies for early CHC screening and rapid treatment are needed to improve survival rates in this population.

Indexed as

Carcinoma, HepatocellularHepatitis C, ChronicLiver NeoplasmsCohort StudiesFemaleHumansMaleOmanTertiary Care Centers

Identifiers

PMID38190454
PMCPMC10852148
OpenAlexW4386864238

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.