Evidence map›Paper›PMID 38190400›Full record

ArticlePLoS computational biology2024

MEDUSA: A cloud-based tool for the analysis of X-ray diffuse scattering to obtain the bending modulus from oriented membrane stacks.

Sebastian Himbert, Dorian Gaboo, Emre Brookes, John F Nagle, Maikel C Rheinstädter

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS computational biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sebastian HimbertDepartment of Physics and Astronomy, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-8193-5654
Dorian GabooDepartment of Physics and Astronomy, McMaster University, Hamilton, Ontario, Canada.
Emre BrookesDepartment of Chemistry and Biochemistry, University of Montana, Missoula, Montana, United States of America.
John F NagleDepartment of Physics, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.
Maikel C RheinstädterDepartment of Physics and Astronomy, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-0558-7475
McMaster University · CACarnegie Mellon University · USUniversity of Montana · US

Funding

Development of an UltraScan Meta-Scheduler for HPC Job SubmissionR01GM120600 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Emre H. Brookes, BORRIES DEMELER · 2016 to 2026
$3.6M
NIGMS NIH HHS R01 GM120600
6 · The paper itself

Abstract

An important mechanical property of cells is their membrane bending modulus, κ. Here, we introduce MEDUSA (MEmbrane DiffUse Scattering Analysis), a cloud-based analysis tool to determine the bending modulus, κ, from the analysis of X-ray diffuse scattering. MEDUSA uses GPU (graphics processing unit) accelerated hardware and a parallelized algorithm to run the calculations efficiently in a few seconds. MEDUSA's graphical user interface allows the user to upload 2-dimensional data collected from different sources, perform background subtraction and distortion corrections, select regions of interest, run the fitting procedure and output the fitted parameters, the membranes' bending modulus κ, and compressional modulus B.

Indexed as

AlgorithmsCloud ComputingRadiographyX-Rays

Identifiers

PMID38190400
PMCPMC10798642
OpenAlexW4390659886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.