Evidence map›Paper›PMID 38189958›Full record

ArticleOrthopadie (Heidelberg, Germany)2024

[Treatment of osteochondritis dissecans].

Franziska Breulmann, Julian Mehl, Alexander Otto, Sebastian Lappen, Sebastian Siebenlist, Peter Rab

Abstract readEnglish Abstract
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In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Franziska BreulmannSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland.
Julian MehlSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland.
Alexander OttoSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland.
Sebastian LappenSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland.
Sebastian SiebenlistSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland. sebastian.siebenlist@mri.tum.de.
Peter RabSektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, 81675, München, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteochondritis dissecans (OD) is a rare condition with an incidence of 30/100,000. It especially affects male patients aged 10-20 years old. During the staged progression the osteochondral fragments can detach from their base. These can damage the adjacent articular cartilage, which can lead to premature osteoarthritis. Most commonly affected are the knee, ankle and elbow joints. The exact pathogenesis of OD has so far not been clearly confirmed. Several risk factors that can lead to the development of OD are discussed. These include repeated microtrauma and vascularization disorders that can lead to ischemia of the subchondral bone and to a separation of the fragments close to the joint and therefore to the development of free joint bodies. For an adequate clarification patients should undergo a thorough radiological evaluation including X‑ray imaging followed by magnetic resonance imaging (MRI) to assess the integrity of the cartilage-bone formation with determination of the OD stage. The assessment is based on criteria of the International Cartilage Repair Society (ICRS). The instability of the cartilage-bone fragment increases with higher stages. Stages I and II with stable cartilage-bone interconnection can be treated conservatively. For stages III and IV, i.e., instability of the OD fragment or the presence of free fragments, surgical treatment should be performed. Primarily, refixation of a free joint body should be carried out depending on the size and vitality of the fragment. In cases of unsuccessful conservative treatment or fixation, a debridement, if necessary in combination with a bone marrow stimulating procedure, can be employed corresponding to the size of the defect. For larger cartilage defects, an osteochondral graft transplantation should be considered. Overall, OD lesions in stages I and II show a good healing tendency under conservative treatment. In cases of incipient unstable OD, refixation can also lead to good clinical and radiological results.

Indexed as

Cartilage, ArticularIntra-Articular FracturesJoint Loose BodiesOsteochondritis DissecansAdolescentAdultAnkle JointChildChondrogenesisConservative TreatmentHumansMaleYoung AdultCartilage-regenerative procedureFixation of osteochondral fragmentsMicrofracturingOsteochondral autologous transplantation(Osteo-)Chondral lesions

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.