Evidence map›Paper›PMID 38189916›Full record

ReviewAnalytical and bioanalytical chemistry2024

Advances in microfluidic technology for sperm screening and in vitro fertilization.

Jingtong Ma, Qianlin Xie, Yusongjia Zhang, Qirui Xiao, Xiaoyu Liu, Chong Qiao, Ye Tian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jingtong MaCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China.
Qianlin XieCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China.
Yusongjia ZhangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China.
Qirui XiaoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China.
Xiaoyu LiuDepartment of Obstetrics and Gynaecology, General Hospital of Northern Theater Command, Shenyang, 110003, China. 328609292@qq.com.
Chong QiaoDepartment of Obstetrics and Gynecology of Shengjing Hospital of China Medical University, Shenyang, 110022, China. qiaochong2002@hotmail.com.
Ye TianCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China. tianye@bmie.neu.edu.cn.
Northeastern University · CNChina Medical University · CNGeneral Hospital of Shenyang Military Region · CN

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2021A1515010130Fundamental Research Funds for the Central Universities N2319005National Natural Science Foundation of China 32201179
6 · The paper itself

Abstract

About 18% of reproductive-age adults worldwide are affected by infertility. In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are widely used assisted reproductive technologies (ARTs) aimed at improving clinical outcomes. Efficient and noninvasive selection and isolation of highly motile sperm with intact DNA are essential for the success of IVF and ICSI and can potentially impact the therapeutic efficacy and the health of the offspring. Compared to traditional methods, microfluidic technology offers significant advantages such as low sample consumption, high efficiency, minimal damage, high integration, similar microenvironment, and high automation, providing a new platform for ARTs. Here, we review the current situation of microfluidic technology in the field of sperm motility screening and evaluation and IVF research. First, we focus on the working principle, structural design, and screening results of sperm selection microfluidic platforms. We then highlight how the multiple steps of the IVF process can be facilitated and integrated into a microfluidic chip, including oocyte capture, sperm collection and isolation, sperm sorting, fertilization, and embryo culture. Ultimately, we summarize how microfluidics can complement and optimize current sperm sorting and IVF protocols, and challenges and possible solutions are discussed.

Indexed as

Fertilization in VitroMicrofluidic Analytical TechniquesSpermatozoaFemaleHumansLab-On-A-Chip DevicesMaleSperm MotilityAssisted reproductive technologies (ARTs)Intracytoplasmic sperm injection (ICSI)In vitro fertilization (IVF)MicrofluidicsSperm screening

Identifiers

PMID38189916
OpenAlexW4390669064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.