Evidence map›Paper›PMID 38189839›Full record

ArticleCurrent microbiology2024

Medium Optimization and Fermentation Kinetics for Antifungal Compounds Production by an Endophytic Paenibacillus polymyxa DS-R5 Isolated from Salvia miltiorrhiza.

Rongbo Sa, Yue Sun, Ying Cao, Wenhui Yan, Zhaohui Zong, Wen An, Meimei Song

Abstract read
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In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rongbo Sa *Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China.ORCID http://orcid.org/0000-0003-2857-3049
Yue Sun *Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China.
Ying CaoTaian Center for Disease Control and Prevention, Taian, China.
Wenhui YanShandong First Medical University & Shandong Academy of Medical Sciences, Taian, China.
Zhaohui ZongShandong First Medical University & Shandong Academy of Medical Sciences, Taian, China.
Wen AnShandong First Medical University & Shandong Academy of Medical Sciences, Taian, China. anwenno1@163.com.
Meimei SongShandong First Medical University & Shandong Academy of Medical Sciences, Taian, China. mmsong.shuxue@163.com.
Shandong First Medical University · CNXian Center for Disease Control and Prevention · CN

Funding

Collaborative Innovation Center for Modern Science and Technology and Industrial Development of Jiangxi Traditional Medicine 2019-0347
6 · The paper itself

Abstract

An endophytic bacterium Paenibacillus polymyxa DS-R5 which can effectively inhibit the growth of pathogenic fungi was isolated from Salvia miltiorrhiza in our previous study. By using hydrochloric acid precipitation, methanol extraction, silica gel column isolation, dextran gel chromatography column, and HPLC, 3 compounds with antifungal activity were isolated. To further improve the production of antifungal compounds produced by this strain, fermentation medium was optimized using one-factor-at-a-time, Plackett-Burman design, and Box-Behnken design experiments. Through statistical optimization, the optimal medium composition was determined to be as follows: 14.7 g/l sucrose, 20.0 g/l soluble starch, 7.0 g/l corn steep liquor, 10.0 g/l (NH

Indexed as

Paenibacillus polymyxaSalvia miltiorrhizaAmniotic FluidAntifungal AgentsFermentationAntifungal Agents

Identifiers

PMID38189839
OpenAlexW4390670323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.