Evidence map›Paper›PMID 38189401›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[Sulforaphane reverses Aβ fiber-mediated M1 type microglia polarization and neuroinflammation-mediated necroptosis of neural stem cells by downregulating the MAPK/NF-κB signaling pathways].

J Zhang, C Yang, S Zhang, T Cao, R Peng, W Guo, Y Yan, S Xie, X Peng, T Lü and 1 more

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

J ZhangDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
C YangDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
S ZhangDepartment of Internal Medicine, Nansha District Second People's Hospital, Guangzhou 511455, China.
T CaoDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
R PengDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
W GuoDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Y YanDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
S XieDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
X PengDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
T LüDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
T HuangDepartment of Neurology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Third Affiliated Hospital of Southern Medical University · CNGuangdong Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of sulforaphane (SFN) and Aβ

methodsBV-2 cells treated with different concentrations of fAβ

resultsfAβ

conclusionSFN reverses M1 type microglia polarization and neuroinflammation-mediated programmed necrosis of neural stem cells by downregulating the MAPK/NF-κB signaling pathway in Aβ

Indexed as

Neural Stem CellsNF-kappa BHumansInterleukin-6IsothiocyanatesMicrogliaNecroptosisNecrosisNeuroinflammatory DiseasesRNA, MessengerSignal TransductionSulfoxidesTumor Necrosis Factor-alphaInterleukin-6IsothiocyanatesNF-kappa BRNA, MessengersulforaphaneSulfoxidesTumor Necrosis Factor-alphaAlzheimer's diseaseM1MAPKmicroglianeural stem cellsneuroinflammationNF-κBsulforaphaneβ-amyloid

Identifiers

PMID38189401
PMCPMC10774108
OpenAlexW4390743925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.