Evidence map›Paper›PMID 38189278›Full record

ArticleAntimicrobial agents and chemotherapy2024

Inhibition of

Rasmus Kristensen, Jens Bo Andersen, Morten Rybtke, Charlotte Uldahl Jansen, Blaine Gabriel Fritz, Rikke Overgaard Kiilerich, Jesper Uhd, Thomas Bjarnsholt, Katrine Qvortrup, Tim Tolker-Nielsen and 2 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Inactivation of MexT inJournal of bacteriology · 2026
    Article
  5. Article
  6. Article
  7. Modulation of themBio · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rasmus KristensenDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.
Jens Bo AndersenDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.
Morten RybtkeDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.
Charlotte Uldahl JansenDepartment of Chemistry, Technical University of Denmark, Lyngby, Denmark.
Blaine Gabriel FritzDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.
Rikke Overgaard KiilerichDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.
Jesper UhdDepartment of Chemistry, Technical University of Denmark, Lyngby, Denmark.
Thomas BjarnsholtDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8003-7414
Katrine QvortrupDepartment of Chemistry, Technical University of Denmark, Lyngby, Denmark.
Tim Tolker-NielsenDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9751-474X
Michael GivskovDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5004-8609
Tim Holm JakobsenDepartment of Immunology and Microbiology, Costerton Biofilm Center, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1671-2155

Funding

Carlsbergfondet (Carlsberg Foundation) CF18-0631Lundbeck Foundation (Lundbeckfonden)
6 · The paper itself

Abstract

The cell-to-cell communication system quorum sensing (QS), used by various pathogenic bacteria to synchronize gene expression and increase host invasion potentials, is studied as a potential target for persistent infection control. To search for novel molecules targeting the QS system in the Gram-negative opportunistic pathogen

Indexed as

Pseudomonas aeruginosaQuorum SensingBacterial ProteinsVirulence FactorsBacterial ProteinsVirulence FactorsMexEF-oprNPseudomonas aeruginosaquorum sensingquorum-sensing inhibitorthiol-reactive compoundvirulence factors

Identifiers

PMID38189278
PMCPMC10848761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.