Evidence map›Paper›PMID 38189271›Full record

ArticlemSystems2024

Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant

Nitasha D Menon, Saugat Poudel, Anand V Sastry, Kevin Rychel, Richard Szubin, Nicholas Dillon, Hannah Tsunemoto, Yujiro Hirose, Bipin G Nair, Geetha B Kumar and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Deciphering the proteome ofComputational and structural biotechnology journal · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Nitasha D MenonSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Saugat PoudelDepartment of Bioengineering, University of California, San Diego, La Jolla, California, USA.
Anand V SastryDepartment of Bioengineering, University of California, San Diego, La Jolla, California, USA.
Kevin RychelDepartment of Bioengineering, University of California, San Diego, La Jolla, California, USA.
Richard SzubinDepartment of Bioengineering, University of California, San Diego, La Jolla, California, USA.
Nicholas DillonDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Hannah TsunemotoDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Yujiro HiroseDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Bipin G NairSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Geetha B KumarSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.ORCID 0000-0002-4584-6929
Bernhard O PalssonDepartment of Bioengineering, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0003-2357-6785
Victor NizetDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0003-3847-0422
University of California San Diego · USAmrita Vishwa Vidyapeetham · INThe University of Texas at Dallas · US

Funding

Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated PneumoniaR01AI176554 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Angela Meier, Victor Nizet · 2023 to 2026
$4.0M
NIAID NIH HHS R01 AI176554NIAID NIH HHS R37 AI052453NIAID NIH HHS U01 AI124316
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsGene Expression RegulationHumansVirulenceAnti-Bacterial AgentsAcinetobacter baumanniiiModulontranscriptional regulation

Identifiers

PMID38189271
PMCPMC10878099
OpenAlexW4390662514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.