Evidence map›Paper›PMID 38188872›Full record

ArticleFrontiers in nutrition2023

Sodium intake and the risk of various types of cardiovascular diseases: a Mendelian randomization study.

Qingming Fu, Rumeng Chen, Yining Ding, Shuling Xu, Chunxia Huang, Binsheng He, Ting Jiang, Bin Zeng, Meihua Bao, Sen Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Qingming Fu *School of Stomatology, Changsha Medical University, Changsha, China.
Rumeng Chen *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yining Ding *School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Shuling XuThe Second Affiliated Hospital of Anhui Medical University, Heifei, China.
Chunxia HuangSchool of Stomatology, Changsha Medical University, Changsha, China.
Binsheng HeThe Hunan Provincial Key Laboratory of the TCM Agricultural Biogenomics, Changsha Medical University, Changsha, China.
Ting JiangSchool of Stomatology, Changsha Medical University, Changsha, China.
Bin ZengSchool of Stomatology, Changsha Medical University, Changsha, China.
Meihua BaoThe Hunan Provincial Key Laboratory of the TCM Agricultural Biogenomics, Changsha Medical University, Changsha, China.
Sen LiSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Changsha Medical University · CNBeijing University of Chinese Medicine · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The existing literature on the link between sodium intake and cardiovascular disease (CVD) largely consists of observational studies that have yielded inconsistent conclusions. In this study, our objective is to assess the causal relationship between sodium intake and 50 CVDs using two-sample Mendelian randomization (MR) analysis. Methods: MR analyses were performed to investigate the associations between urinary sodium/creatinine ratio (U Results: The inverse-variance weighted method indicated that the genetically predicted U Conclusion: Our study has uncovered a significant positive causal relationship between U

Indexed as

cardiovascular diseaseFinnGenMendelian randomizationsodium intakeUK Biobank

Identifiers

PMID38188872
PMCPMC10771828
OpenAlexW4390111420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.