Evidence map›Paper›PMID 38188637›Full record

ArticleInternational journal of cardiology. Cardiovascular risk and prevention2024

Effectiveness of cardiac rehabilitation programs on medication adherence in patients with cardiovascular disease: A systematic review and meta-analysis.

Lemlem Gebremedhin Gebremichael, Stephanie Champion, Katie Nesbitt, Vincent Pearson, Norma B Bulamu, Hila A Dafny, Shelda Sajeev, Maria Alejandra Pinero de Plaza, Joyce S Ramos, Orathai Suebkinorn and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Cardiovascular risk and prevention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Lemlem Gebremedhin GebremichaelCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Stephanie ChampionCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Katie NesbittCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Vincent PearsonJBI, School of Public Health, The University of Adelaide, Australia.
Norma B BulamuFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
Hila A DafnyCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Shelda SajeevCentre for Artificial Intelligence Research and Optimisation (AIRO), Torrens University, Adelaide, South Australia, Australia.
Maria Alejandra Pinero de PlazaCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Joyce S RamosCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Orathai SuebkinornCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Aarti GulyaniCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Lemma N BultoCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Alline BeleigoliCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Jeroen M HendriksCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
Sonia HinesMparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Australia.
Robyn A ClarkCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia.
NHMRC CHAP Project Team
Flinders University · AURoyal Adelaide Hospital · AUThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Education to improve medication adherence is one of the core components of cardiac rehabilitation (CR) programs. However, the evidence on the effectiveness of CR programs on medication adherence is conflicting. Therefore, we aimed to summarize the effectiveness of CR programs versus standard care on medication adherence in patients with cardiovascular disease. Methods: A systematic review and meta-analysis was conducted. Seven databases and clinical trial registries were searched for published and unpublished articles from database inception to 09 Feb 2022. Only randomised controlled trials and quasi-experimental studies were included. Two independent reviewers conducted the screening, extraction, and appraisal. The JBI methodology for effectiveness reviews and PRISMA 2020 guidelines were followed. A statistical meta-analysis of included studies was pooled using RevMan version 5.4.1. Results: In total 33 studies were included with 16,677 participants. CR programs increased medication adherence by 14 % (RR = 1.14; 95 % CI: 1.07 to 1.22; p = 0.0002) with low degree of evidence certainty. CR also lowered the risk of dying by 17 % (RR = 0.83; 95 % CI: 0.69 to 1.00; p = 0.05); primary care and emergency department visit by mean difference of 0.19 (SMD = -0.19; 95 % CI: -0.30 to -0.08; p = 0.0008); and improved quality of life by 0.93 (SMD = 0.93; 95 % CI: 0.38 to 1.49; p = 0.0010). But no significant difference was observed in lipid profiles, except with total cholesterol (SMD = -0.26; 95 % CI: -0.44 to -0.07; p = 0.006) and blood pressure levels. Conclusions: CR improves medication adherence with a low degree of evidence certainty and non-significant changes in lipid and blood pressure levels. This result requires further investigation.

Indexed as

Cardiac rehabilitationClinical outcomesEffectivenessMedication adherenceStandard careSystematic review

Identifiers

PMID38188637
PMCPMC10770721
OpenAlexW4389611985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.