Evidence map›Paper›PMID 38188606›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2024

Participant completion of longitudinal assessments in an online cognitive aging registry: The role of medical conditions.

Miriam T Ashford, Chengshi Jin, John Neuhaus, Adam Diaz, Anna Aaronson, Rachana Tank, Joseph Eichenbaum, Monica R Camacho, Juliet Fockler, Aaron Ulbricht and 6 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Miriam T AshfordVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Chengshi JinUniversity of California San Francisco Department of Epidemiology and Biostatistics San Francisco San Francisco California USA.
John NeuhausUniversity of California San Francisco Department of Epidemiology and Biostatistics San Francisco San Francisco California USA.
Adam DiazVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Anna AaronsonVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Rachana TankDepartment of Radiology and Biomedical Imaging University of California San Francisco California USA.
Joseph EichenbaumVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Monica R CamachoVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Juliet FocklerDepartment of Veterans Affairs Medical Center Northern California Institute for Research and Education (NCIRE) San Francisco California USA.
Aaron UlbrichtDepartment of Veterans Affairs Medical Center Northern California Institute for Research and Education (NCIRE) San Francisco California USA.
Derek FlennikenVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Diana TruranVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Robert Scott MackinVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Michael W WeinerVA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center San Francisco California USA.
Monica Rivera MindtPsychology, Latin American Latino Studies Institute & African and African American Studies Fordham University Joint Appointment in Neurology Icahn School of Medicine at Mount Sinai - New York New York New York USA.
Rachel L NoshenyDepartment of Veterans Affairs Medical Center Northern California Institute for Research and Education (NCIRE) San Francisco California USA.
University of California, San Francisco · USNorthern California Institute for Research and Education · USAdvanced Imaging Research (United States) · USFordham University · USSan Francisco VA Medical Center · USUK Dementia Research Institute · GB

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MICHAEL W WEINER · 2016 to 2026
$226.7M
The Alzheimer's Clinical Trial Consortium - Down Syndrome Network (ACTC- DSN)U24AG057437 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Paul S. Aisen, RONALD C PETERSEN · 2018 to 2026
$198.4M
Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's DiseaseR01AG053798 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AISEN, PAUL S., CUMMINGS, JEFFREY L. · 2017 to 2022
$39.4M
The MobileToolbox for Monitoring Cognitive Function - Technical CoreU2CAG060426 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD GERSHON · 2018 to 2026
$35.0M
Establishing the science behind Alzheimer's recruitment registries: opportunities for increasing diversity and accelerating enrollment into trialsR01AG063954 · NIA · BANNER HEALTH · PI BLEAKLEY, AMY, LANGBAUM, JESSICA BROOKE · 2019 to 2023
$9.6M
Validation of Online Methods to Predict and Monitor Cognitive DeclineRF1AG059009 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOSHENY, RACHEL LAUREN · 2018 to 2018
$6.2M
Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)R01NS119651 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ALOSCO, MICHAEL · 2021 to 2025
$3.9M
The Brain Health Registry for facilitating interdisciplinary aging researchR33AG062867 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOSHENY, RACHEL LAUREN · 2020 to 2024
$3.2M
Inclusion and participation of older adults from underrepresented populations in cognitive aging and Alzheimer's disease-related researchF32AG072730 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI ASHFORD, MIRIAM · 2021 to 2023
$226k
NIA NIH HHS F32 AG072730NIA NIH HHS R01 AG053798NIA NIH HHS R01 AG063954NIA NIH HHS R33 AG062867NIA NIH HHS RF1 AG059009NIA NIH HHS U19 AG024904NIA NIH HHS U24 AG057437NIA NIH HHS U2C AG060426NINDS NIH HHS R01 NS119651
6 · The paper itself

Abstract

introductionThis study aimed to understand whether older adults' longitudinal completion of assessments in an online Alzheimer's disease and related dementias (ADRD)-related registry is influenced by self-reported medical conditions.

methodsBrain Health Registry (BHR) is an online cognitive aging and ADRD-related research registry that includes longitudinal health and cognitive assessments. Using logistic regressions, we examined associations between longitudinal registry completion outcomes and self-reported (1) number of medical conditions and (2) eight defined medical condition groups (cardiovascular, metabolic, immune system, ADRD, current psychiatric, substance use/abuse, acquired, other specified conditions) in adults aged 55+ (

resultsWe found that the likelihood of longitudinally completing the initial questionnaire was negatively associated with reporting a diagnosis of ADRD and current psychiatric conditions but was positively associated with reporting substance use/abuse and acquired medical conditions. The likelihood of longitudinally completing the cognitive assessment task was negatively associated with number of reported medical conditions, as well as with reporting cardiovascular conditions, ADRD, and current psychiatric conditions. Previously identified associations between ethnocultural identity and longitudinal assessment completion in BHR remained after accounting for the presence of medical conditions. DISCUSSION: This post hoc analysis provides novel, initial evidence that older adults' completion of longitudinal assessments in an online registry is associated with the number and types of participant-reported medical conditions. Our findings can inform future efforts to make online studies with longitudinal health and cognitive assessments more usable for older adults with medical conditions. The results need to be interpreted with caution due to selection biases, and the under-inclusion of minoritized communities.

Indexed as

aging researchBrain Health Registrycomorbiditiesdementiaengagementinternet registryneuropsychological testsonlineremote assessmentretention

Identifiers

PMID38188606
PMCPMC10767283
OpenAlexW4390609090

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.