Evidence map›Paper›PMID 38188599›Full record

ArticleImmune network2023

Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells.

Jooyeon Lee, Jimin Jang, Sang-Ryul Cha, Se Bi Lee, Seok-Ho Hong, Han-Sol Bae, Young Jin Lee, Se-Ran Yang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jooyeon LeeDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-4681-7046
Jimin JangDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-1796-2164
Sang-Ryul ChaDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-9447-6434
Se Bi LeeDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0003-4691-8127
Seok-Ho HongDepartment of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0003-3372-442X
Han-Sol BaeCellular Therapeutics Team, Daewoong Pharmaceutical, Yongin 17028, Korea.ORCID https://orcid.org/0009-0000-5024-3949
Young Jin LeeCellular Therapeutics Team, Daewoong Pharmaceutical, Yongin 17028, Korea.ORCID https://orcid.org/0000-0002-2325-5271
Se-Ran YangDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-2422-213X
Kangwon National University · KRDaewoong Pharmaceutical (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stromal/stem cells (MSCs) possess immunoregulatory properties and their regulatory functions represent a potential therapy for acute lung injury (ALI). However, uncertainties remain with respect to defining MSCs-derived immunomodulatory pathways. Therefore, this study aimed to investigate the mechanism underlying the enhanced effect of human recombinant bone morphogenic protein-2 (rhBMP-2) primed ES-MSCs (MSC

Indexed as

Acute lung injuryIndoleamine-pyrrole 2,3,-dioxygenaseMesenchymal stem cellsRecombinant human bone morphogenetic protein-2Regulatory T-cells

Identifiers

PMID38188599
PMCPMC10767548
OpenAlexW4390270128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.