Evidence map›Paper›PMID 38188598›Full record

ArticleImmune network2023

Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and Anti-Apoptotic Mechanisms.

Hanna Lee, Ok-Yi Jeong, Hee Jin Park, Sung-Lim Lee, Eun-Yeong Bok, Mingyo Kim, Young Sun Suh, Yun-Hong Cheon, Hyun-Ok Kim, Suhee Kim and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Hanna LeeDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon 51427, Korea.ORCID https://orcid.org/0000-0002-2129-4269
Ok-Yi JeongDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0001-9362-2746
Hee Jin ParkDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0001-9415-9802
Sung-Lim LeeCollege of Veterinary Medicine and Research Institute of Life Sciences, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-1055-8097
Eun-Yeong BokCollege of Veterinary Medicine and Research Institute of Life Sciences, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-1045-9670
Mingyo KimDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0003-3744-8522
Young Sun SuhDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon 51427, Korea.ORCID https://orcid.org/0000-0002-5378-2590
Yun-Hong CheonDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0002-0099-6253
Hyun-Ok KimDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon 51427, Korea.ORCID https://orcid.org/0000-0002-0904-1584
Suhee KimDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0002-9315-0360
Sung Hak ChunDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0009-0007-3852-6066
Jung Min ParkDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0009-0006-5977-7801
Young Jin LeeCell Therapy Center, Daewoong Pharmaceutical, Co., Ltd., Yongin 17028, Korea.ORCID https://orcid.org/0000-0002-2325-5271
Sang-Il LeeDepartment of Internal Medicine and Institute of Medical Science, Gyeongsang National University School of Medicine and Hospital, Jinju 52727, Korea.ORCID https://orcid.org/0000-0002-8283-7001
Gyeongsang National University Hospital · KRChangwon National University · KRGyeongsang National University · KRDaewoong Pharmaceutical (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) show potential in ILD therapeutics but obtaining an adequate quantity of cells for drug application is difficult. Daewoong Pharmaceutical's MSCs (DW-MSCs) derived from embryonic stem cells sustain a high proliferative capacity following long-term culture and expansion. The aim of this study was to investigate the therapeutic potential of DW-MSCs in experimental mouse models of ILD. DW-MSCs were expanded up to 12 passages for

Indexed as

ApoptosisImmunomodulationInterstitial lung diseaseMesenchymal stem cellMitochondria

Identifiers

PMID38188598
PMCPMC10767550
OpenAlexW4390270099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.