Evidence map›Paper›PMID 38188524›Full record

ArticleiScience2024

Voluntary wheel running improves molecular and functional deficits in a murine model of facioscapulohumeral muscular dystrophy.

Adam J Bittel, Daniel C Bittel, Heather Gordish-Dressman, Yi-Wen Chen

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. IncreasedInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Muscular Dystrophies.Advances in experimental medicine and biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adam J BittelCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Daniel C BittelCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Heather Gordish-DressmanCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Yi-Wen ChenCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Children's National · US

Funding

Genetics and Genomics of Muscle Postdoctoral Training ProgramT32AR056993 · NIAMS · CHILDREN'S RESEARCH INSTITUTE · PI JAISWAL, JYOTI K, PARTRIDGE, TERENCE A · 2010 to 2019
$2.2M
Investigating membrane repair capacity in facioscapulohumeral muscular dystrophyR21HD103993 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI CHEN, YI-WEN · 2021 to 2022
$491k
Investigating proteostasis in facioscapulohumeral muscular dystrophyR21AR080887 · NIAMS · CHILDREN'S RESEARCH INSTITUTE · PI CHEN, YI-WEN · 2022 to 2023
$383k
NIAMS NIH HHS R21 AR080887NIAMS NIH HHS T32 AR056993NICHD NIH HHS R21 HD103993
6 · The paper itself

Abstract

Endurance exercise training is beneficial for skeletal muscle health, but it is unclear if this type of exercise can target or correct the molecular mechanisms of facioscapulohumeral muscular dystrophy (FSHD). Using the FLExDUX4 murine model of FSHD characterized by chronic, low levels of pathological double homeobox protein 4 (

Indexed as

Biological sciencesPathophysiologyTranscriptomics;

Identifiers

PMID38188524
PMCPMC10770537
OpenAlexW4389268405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.