Evidence map›Paper›PMID 38188520›Full record

ArticleiScience2024

Diverse bacteria elicit distinct neutrophil responses in a physiologically relevant model of infection.

Isaac M Richardson, Christopher J Calo, Eric L Ginter, Elise Niehaus, Kayla A Pacheco, Laurel E Hind

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Leveraging Microphysiological Systems to Facilitate Neutrophil-Based Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isaac M RichardsonDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
Christopher J CaloDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
Eric L GinterDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
Elise NiehausDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
Kayla A PachecoDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
Laurel E HindDepartment of Chemical and Biological Engineering, University of Colorado - Boulder, Boulder, CO 80303, USA.
University of Colorado Boulder · US

Funding

Reconstructing Cell-Cell Interactions in Diverse Inflammatory EnvironmentsR35GM146737 · NIGMS · UNIVERSITY OF COLORADO · PI Laurel Erin Hind · 2022 to 2026
$2.1M
NIGMS NIH HHS R35 GM146737
6 · The paper itself

Abstract

An efficient neutrophil response is critical for fighting bacterial infections, which remain a significant global health concern; therefore, modulating neutrophil function could be an effective therapeutic approach. While we have a general understanding of how neutrophils respond to bacteria, how neutrophil function differs in response to diverse bacterial infections remains unclear. Here, we use a microfluidic infection-on-a-chip device to investigate the neutrophil response to four bacterial species:

Indexed as

BacteriologyImmunology

Identifiers

PMID38188520
PMCPMC10770534
OpenAlexW4389273935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.