Evidence map›Paper›PMID 38188511›Full record

ArticleiScience2024

Numerical investigation of a graphene-on-semiconductor device for optical monitoring of cell electrophysiology.

Jon Gorecki, Steffi Krause

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jon GoreckiDepartment of Bioengineering, Imperial College London, Exhibition Road, London SW7 2BX, UK.
Steffi KrauseSchool of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK.
Imperial College London · GBQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatially resolved sensing devices for electrostatic potentials are extremely useful for characterization of living cells, however, many current techniques lack the speed necessary to capture spatially resolved, functional information of cells in real-time. Here, an optical sensing technique is proposed based on graphene on a semiconductor stack operating in the near-infrared spectrum. By modeling coherent interference of multiply reflected beam paths within the semiconductor stack, we demonstrate how the device produces a continuous reflectivity change in response to graphene Fermi energy which is ideal for sensing changes in local electrostatic fields produced by action potentials of living cells. By coupling the device with a high-speed camera, we propose this platform will allow for high-speed imaging of action potentials over a large sensing area with micron scale resolution.

Indexed as

Biomedical materialsDevicesMaterials physicsMaterials science

Identifiers

PMID38188511
PMCPMC10770480
OpenAlexW4388979317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.