Evidence map›Paper›PMID 38188260›Full record

ArticleRSC advances2024

Green synthesis of chlorella-derived carbon dots and their fluorescence imaging in zebrafish.

Yue Wang, Zhihi Gu, Jingyi Dong, Jie Zhu, Cunguang Liu, Guohan Li, Meichen Lu, Jian Han, Shengnan Cao, Liyong Chen and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yue WangKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Zhihi GuKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.ORCID https://orcid.org/0009-0003-7382-2961
Jingyi DongKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Jie ZhuKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Cunguang LiuKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Guohan LiKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Meichen LuKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Jian HanKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Shengnan CaoKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Liyong ChenDepartment of Pharmaceutical Engineering, Bengbu Medical College Bengbu 233030 China.ORCID https://orcid.org/0000-0002-6735-9195
Wei WangKey Laboratory of Applied Biology and Aquaculture of Northern Fishes in Liaoning Province, Dalian Ocean University Dalian 116023 China guzhizhi@dlou.edu.cn wangwei@dlou.edu.cn.
Dalian Ocean University · CNBengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, carbon dots (CDs) have been shown to exhibit exceptional water solubility, low toxicity, favorable biocompatibility, stable fluorescence properties with a wide and continuous excitation spectrum, and an adjustable emission spectrum. Their remarkable characteristics make them highly promising for applications in the field of bioimaging. Zebrafish is currently extensively studied because of its high genetic homology with humans and the applicability of disease research findings from zebrafish to humans. Therefore, spirulina, a commonly used feed additive in aquaculture, was chosen as the raw material for synthesizing fluorescent CDs using a hydrothermal method. On the one hand, CDs can modulate dopamine receptors in the brain of zebrafish, leading to an increase in dopamine production and subsequently promoting their locomotor activity. On the other hand, CDs have been shown to enhance the intestinal anti-inflammatory capacity of zebrafish. This study aimed to explore the chronic toxicity and genotoxicity of CDs in zebrafish while providing valuable insights for their future application in biological and medical fields.

Identifiers

PMID38188260
PMCPMC10768801
OpenAlexW4390618258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.