Evidence map›Paper›PMID 38188172›Full record

ArticlePeerJ2024

Enrichment of polycyclic aromatic hydrocarbon metabolizing microorganisms on the oral mucosa of tobacco users.

Lin Tao, M Paul Chiarelli, Sylvia Pavlova, Antonia Kolokythas, Joel Schwartz, James DeFrancesco, Benjamin Salameh, Stefan J Green, Guy Adami

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lin Tao *Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL, United States of America.
M Paul Chiarelli *Department of Chemistry and Biochemistry, Loyola University of Chicago, Chicago, IL, United States of America.
Sylvia PavlovaDepartment of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL, United States of America.
Antonia KolokythasDepartment of Oral and Maxillofacial Surgery, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, United States of America.
Joel SchwartzOral Medicine and Diagnostic Sciences, University of Illinois Chicago, Chicago, IL, United States of America.
James DeFrancescoForensic Science Program - Department of Criminal Justice, Loyola University of Chicago, Chicago, IL, United States of America.
Benjamin SalamehOral Medicine and Diagnostic Sciences, University of Illinois Chicago, Chicago, IL, United States of America.
Stefan J GreenDNA Sequencing Core, Research Resources Center, University of Illinois Chicago, Chicago, IL, United States of America.
Guy AdamiOral Medicine and Diagnostic Sciences, University of Illinois Chicago, Chicago, IL, United States of America.
University of Illinois Chicago · USEastman Chemical Company (United States) · USLoyola University Chicago · USUniversity of Chicago · US

Funding

Microbial Surrogate Assay for Environmental PAH ExposureR41ES025528 · NIEHS · ARPHION, LTD · PI ADAMI, GUY RICHARD · 2014 to 2014
$149k
NIEHS NIH HHS R41 ES025528
6 · The paper itself

Abstract

Certain soil microbes resist and metabolize polycyclic aromatic hydrocarbons (PAHs). The same is true for a subset of skin microbes. In the human mouth, oral microbes have the potential to oxidize tobacco PAHs, thereby increasing these chemicals' ability to cause cancer of adjacent epithelium. We hypothesized that we could identify, in smokers, the oral mucosal microbes that can metabolize PAH. We isolated bacteria and fungi that survived long-term in minimal media with PAHs as the sole carbon source, under aerobic conditions, from the oral mucosa in 17 of 26 smokers and two of 14 nonsmokers. Of bacteria genera that survived harsh PAH exposure

Indexed as

Mouth MucosaPolycyclic Aromatic HydrocarbonsCandidaCandida albicansHumansMouthTobacco ProductsPolycyclic Aromatic HydrocarbonsCandida albicansKingellaMicroccous luteusMycobacterium rutilumPAH metabolismPolycyclic aromatic hydrocarbons

Identifiers

PMID38188172
PMCPMC10771095
OpenAlexW4390544774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.