Evidence map›Paper›PMID 38188142›Full record

ArticlePeerJ2024

Evaluating the relationship between Clinical G6PD enzyme activity and gene variants.

Xinyi Zhou, Zheng Qiang, Sufen Zhang, Yuqiu Zhou, Qizhi Xiao, Gongjun Tan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xinyi Zhou *Department of Clinical Laboratory & Zhuhai Institute of Medical Genetics, Zhuhai Maternity and Child Healthcare Hospital, Zhuhai, Guangdong, China.
Zheng Qiang *Pathology Department, Zhuhai Maternity and Child Healthcare Hospital, Zhuhai, China.
Sufen ZhangDepartment of Clinical Laboratory & Zhuhai Institute of Medical Genetics, Zhuhai Maternity and Child Healthcare Hospital, Zhuhai, Guangdong, China.
Yuqiu ZhouDepartment of Clinical Laboratory & Zhuhai Institute of Medical Genetics, Zhuhai Maternity and Child Healthcare Hospital, Guangdong, China.
Qizhi XiaoDepartment of Clinical Laboratory & Zhuhai Institute of Medical Genetics, Zhuhai Maternity and Child Healthcare Hospital, Zhuhai, Guangdong, China.
Gongjun TanDepartment of Clinical Laboratory & Zhuhai Institute of Medical Genetics, Zhuhai Maternity and Child Healthcare Hospital, Zhuhai, Guangdong, China.
Weihai Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) is a the first and rate-limiting enzyme that plays a critical role in G6PD deficiency, the most common enzyme disorder worldwide, is related to intravascular hemolysis. To determine the clinical enzyme activity level in different G6PD variants, we evaluated 15 variant from 424 clinical blood samples by using multicolor melting curve analysis and DNA sequencing. The results showed that the enzyme activities of the hemizygous deficient were 1.5-2.4 U/gHb, which was significantly lower than those of the heterozygous (

Indexed as

Glucosephosphate Dehydrogenase DeficiencyGenotypeHematologic TestsHumansEnzyme activitiesG6PDGenetic variants

Identifiers

PMID38188142
PMCPMC10771088
OpenAlexW4390544677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.