Evidence map›Paper›PMID 38187924›Full record

ArticleFrontiers in behavioral neuroscience2023

Identification of neural circuits controlling male sexual behavior and sexual motivation by manganese-enhanced magnetic resonance imaging.

Lorena Gaytán-Tocavén, Alejandro Aguilar-Moreno, Juan Ortiz, Sarael Alcauter, Edwards Antonio-Cabrera, Raúl G Paredes

Abstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorena Gaytán-TocavénEscuela Nacional de Estudios Superiores, Unidad Juriquilla, UNAM, Querétaro, Mexico.
Alejandro Aguilar-MorenoInstituto de Neurobiología, UNAM, Querétaro, Mexico.
Juan OrtizInstituto de Neurobiología, UNAM, Querétaro, Mexico.
Sarael AlcauterInstituto de Neurobiología, UNAM, Querétaro, Mexico.
Edwards Antonio-CabreraInstituto de Neurobiología, UNAM, Querétaro, Mexico.
Raúl G ParedesEscuela Nacional de Estudios Superiores, Unidad Juriquilla, UNAM, Querétaro, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Different techniques have been used to identify the brain regions that control sexual motivation and sexual behavior. However, the influence of sexual experience on the activation of these brain regions in the same subject is unknown. Using manganese-enhanced magnetic resonance imaging (MEMRI), we analyzed the activation of brain regions in the sexual incentive motivation (SIM) and the partner preference PP (tests) on weeks 1, 5, and 10 in male rats tested for 10 weeks. AIM. In experiment 1, we analyzed the possible toxic effects of 16 mg/kg of MnCl Methods: In both experiments, a dose of 16 mg/kg (s.c) of chloride manganese (MnCl Results: In experiment 1, the dose of 16 mg/kg of MnCl Discussion: As the subjects gain sexual experience, more structures of the reward and socio-sexual circuits are recruited, resulting in different, and large brain activations.

Indexed as

manganeseMEMRIneural circuitssexual behaviorsexual motivation

Identifiers

PMID38187924
PMCPMC10768062

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.