Evidence map›Paper›PMID 38187699›Full record

ArticlebioRxiv : the preprint server for biology2023

Temporal recording of mammalian development and precancer.

Mirazul Islam, Yilin Yang, Alan J Simmons, Vishal M Shah, Musale Krushna Pavan, Yanwen Xu, Naila Tasneem, Zhengyi Chen, Linh T Trinh, Paola Molina and 15 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 3 countries.

Yilin Yang
Alan J Simmons
Vishal M Shah
Musale Krushna Pavan
Yanwen Xu
Naila Tasneem
Zhengyi Chen
Linh T Trinh
Paola Molina
Marisol A Ramirez-Solano
Iannish Sadien
Jinzhuang Dou
Ken Chen
Jeffrey C RathmellORCID 0000-0002-4106-3396
Ian G Macara
Douglas Winton
Qi Liu
Hamim Zafar
Reza Kalhor
George M Church
Martha J Shrubsole
Vanderbilt University · USVanderbilt University Medical Center · USIndian Institute of Technology Kanpur · INThe University of Texas MD Anderson Cancer Center · USUniversity of Cambridge · GBHarvard University · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key to understanding many biological phenomena is knowing the temporal ordering of cellular events, which often require continuous direct observations [1, 2]. An alternative solution involves the utilization of irreversible genetic changes, such as naturally occurring mutations, to create indelible markers that enables retrospective temporal ordering [3-8]. Using NSC-seq, a newly designed and validated multi-purpose single-cell CRISPR platform, we developed a molecular clock approach to record the timing of cellular events and clonality

Identifiers

PMID38187699
PMCPMC10769302
OpenAlexW4389981279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.