Evidence map›Paper›PMID 38187698›Full record

ArticlebioRxiv : the preprint server for biology2023

VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1.

Berrak Ugur, Florian Schueder, Jimann Shin, Michael G Hanna, Yumei Wu, Marianna Leonzino, Maohan Su, Anthony R McAdow, Catherine Wilson, John Postlethwait and 3 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Berrak UgurDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-4806-8891
Florian SchuederDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-3412-5066
Jimann ShinDepartment of Developmental Biology, Washington University School of Medicine, St Louis, MO, USA.
Michael G HannaDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Yumei WuDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Marianna LeonzinoDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Maohan SuDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Anthony R McAdowDepartment of Developmental Biology, Washington University School of Medicine, St Louis, MO, USA.
Catherine WilsonInstitute of Neuroscience, University of Oregon, Eugene, OR, USA.
John PostlethwaitInstitute of Neuroscience, University of Oregon, Eugene, OR, USA.
Lilianna Solnica-KrezelDepartment of Developmental Biology, Washington University School of Medicine, St Louis, MO, USA.
Joerg BewersdorfDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-4085-7020
Pietro De CamilliDepartment of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9045-0723
Yale University · USWashington University in St. Louis · USUniversity of Oregon · US

Funding

Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI ANGUS C. NAIRN, Kenneth Robert WILLIAMS · 2004 to 2026
$37.1M
Resources for Teleost Gene Duplicates and Human DiseaseR01OD011116 · OD · UNIVERSITY OF OREGON · PI POSTLETHWAIT, JOHN H. · 2012 to 2020
$5.4M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 1997 to 2021
$4.7M
Multi-organism platform for functional assessment of human birth defect associated genomic variantsR01HD110556 · NICHD · WASHINGTON UNIVERSITY · PI AARON N JOHNSON, Kristen L Kroll · 2023 to 2026
$2.5M
Development of a Versatile Multiplexing Nanoscopy Platform for Cell BiologyR01GM151829 · NIGMS · YALE UNIVERSITY · PI Joerg Bewersdorf · 2023 to 2026
$2.3M
NICHD NIH HHS R01 HD110556NIDA NIH HHS P30 DA018343NIGMS NIH HHS R01 GM151829NIH HHS R01 OD011116NINDS NIH HHS R01 NS036251
6 · The paper itself

Abstract

Mutations in VPS13B, a member of a protein family implicated in bulk lipid transport between adjacent membranes, cause Cohen syndrome. VPS13B is known to be concentrated in the Golgi complex, but its precise location within this organelle and thus the site(s) where it achieves lipid transport remains unclear. Here we show that VPS13B is localized at the interface between cis and trans Golgi sub-compartments and that Golgi complex re-formation after Brefeldin A (BFA) induced disruption is delayed in

Identifiers

PMID38187698
PMCPMC10769246
OpenAlexW4389903301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.